Results 61 to 70 of about 400,828 (294)

Development of a vehicle robotic driver with intelligent control system modelling for automated standard driving-cycle tests [PDF]

, 2019
New road vehicles are required to undergo several specific tests to meet the requirement set by governing bodies in various markets. These tests are often carried out over specific driving-cycles.
Mohammed Mahdi, Ammar Abdo
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Novel Map Platform based on Primitive Elements of Traffic Environments for Automated Driving Technologies

International Journal of Automotive Engineering, 2016
To realize driver assistance systems based on automated driving technologies, intelligent vehicles need to recognize surrounding driving environments.
Takuma Ito, Masahiro Mio, Kyoichi Tohriyama, Minoru Kamata   +3 more
doaj   +1 more source

Design Criteria to Architect Continuous Experimentation for Self-Driving Vehicles

, 2017
The software powering today's vehicles surpasses mechatronics as the dominating engineering challenge due to its fast evolving and innovative nature.
Berger, Christian, Giaimo, Federico
core   +1 more source

Concurrent Optimization of Vehicle Dynamics and Powertrain Operation Using Connectivity and Automation

, 2020
Connected and automated vehicles (CAVs) provide the most intriguing opportunity to reduce energy consumption and travel delays. In this paper, we propose a two-level control architecture for CAVs to optimize (1) the vehicle's speed profile, aimed at ...
Mahbub, A M Ishtiaque, Malikopoulos, Andreas A.   +1 more
core   +1 more source

In loco intellegentia: Human factors for the future European train driver [PDF]

, 2006
The European Rail Traffic Management System (ERTMS) represents a step change in technology for rail operations in Europe. It comprises track-to-train communications and intelligent on-board systems providing an unprecedented degree of support to the ...
Stanton, NA, Walker, GH, Young, MS
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Automated Driving System Challenges in Rural Appalachia

IEEE Open Journal of Intelligent Transportation Systems
The development of autonomous driving technology has predominantly focused on urban and suburban areas. Deployment of automated driving systems in regions such as rural Appalachia present unique challenges such as narrow and winding roads and degradation
Michael A. Tonkovich, Travis W. Moleski, Sam Fayez, Andrew Wallace, Preeti Choudhary, Jay P. Wilhelm   +5 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source