Results 31 to 40 of about 10,135,005 (257)

Adapting Land Use and Infrastructure for Automated Driving: Part A [PDF]

69A3551747105This project is concerned with adapting land use and transportation infrastructure for automated driving. Autonomous vehicles will likely yield a transformation of urban form, its land use and mobility system.
University of Michigan, Ann Arbor, Yin, Yafeng, Center for Connected and Automated Transportation (CCAT)   +2 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Novel Map Platform based on Primitive Elements of Traffic Environments for Automated Driving Technologies

International Journal of Automotive Engineering, 2016
To realize driver assistance systems based on automated driving technologies, intelligent vehicles need to recognize surrounding driving environments.
Takuma Ito, Masahiro Mio, Kyoichi Tohriyama, Minoru Kamata   +3 more
doaj   +1 more source

Usability Evaluation—Advances in Experimental Design in the Context of Automated Driving Human–Machine Interfaces

Information, 2020
The projected introduction of conditional automated driving systems to the market has sparked multifaceted research on human–machine interfaces (HMIs) for such systems.
Deike Albers, Jonas Radlmayr, Alexandra Loew, Sebastian Hergeth, Frederik Naujoks, Andreas Keinath, Klaus Bengler   +6 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

A Driving Simulator Investigation on the Aggressiveness of an Automatic Lane-Change System

IEEE Access
Most existing personalized automatic lane-change systems rely on manual driving data, but obtaining such data for future highly automated driving systems will become increasingly difficult.
Muhua Guan, Zheng Wang, Bo Yang, Chenchang Li, Kimihiko Nakano   +4 more
doaj   +1 more source

Scared to Trust? – Predicting Trust in Highly Automated Driving by Depressiveness, Negative Self-Evaluations and State Anxiety

Frontiers in Psychology, 2020
The advantages of automated driving can only come fully into play if these systems are used in an appropriate way, which means that they are neither used in situations they are not designed for (misuse) nor used in a too restricted manner (disuse). Trust
Johannes Kraus, David Scholz, Eva-Maria Messner, Matthias Messner, Martin Baumann   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A Dataset on Takeover during Distracted L2 Automated Driving

Scientific Data
Automated driving systems enable drivers to perform various non-driving tasks, which has led to concerns regarding driver distraction during automated driving.
Jiwoo Hwang, Woohyeok Choi, Jungmin Lee, Woojoo Kim, Jungwook Rhim, Auk Kim   +5 more
doaj   +1 more source