Results 91 to 100 of about 104,763 (297)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Evaluation of an Automated Digital Scoring System of Dental Plaque.

open access: yes, 2020
Purpose: Measurement of dental plaque is frequently used as an indicator of overall oral health. The purpose of this study was to compare a manual (visual) plaque scoring system (University of Mississippi Oral Hygiene Index, UM-OHI) with an innovative ...
Munro, Cindy L.
core   +1 more source

Automated Graphic Divergent Thinking Assessment: A Multimodal Machine Learning Approach

open access: yesJournal of Intelligence
This study proposes a multimodal deep learning model for automated scoring of image-based divergent thinking tests, integrating visual and semantic features to improve assessment objectivity and efficiency.
Hezhi Zhang   +6 more
doaj   +1 more source

The Influence of Bureau Scores, Customized Scores and Judgmental Review on the Bank Underwriting Decision-Making Process [PDF]

open access: yes
In recent years commercial banks have moved toward automated forms of underwriting. This study employs unique bank loan-level data from a scoring lender to determine whether automated underwriting exhibits a potential ‘‘disparate impact’’ across income ...
M. Cary Collins   +2 more
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Improving automated scoring of prosody in oral reading fluency using deep learning algorithm

open access: yesFrontiers in Education
Automated assessing prosody of oral reading fluency presents challenges due to the inherent difficulty of quantifying prosody. This study proposed and evaluated an approach focusing on specific prosodic features using a deep-learning neural network.
Kuo Wang   +5 more
doaj   +1 more source

Automated Essay Scoring for Swedish.

open access: yes, 2013
We present the first system developed for automated grading of high school essays written in Swedish. The system uses standard text quality indicators and is able to compare vocabulary and grammar to large reference corpora of blog posts and newspaper articles.
Östling, Robert   +3 more
openaire   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Automated Scoring of Scientific Creativity in German

open access: yes
Automated scoring is a current hot topic in creativity research. However, most research has focused on the English language and popular verbal creative thinking tasks, such as the alternate uses task. Therefore, in this study, we present a large language
Roger Beaty   +5 more
core   +3 more sources

Real-Time Automated Answer Scoring

open access: yes2018 IEEE 18th International Conference on Advanced Learning Technologies (ICALT), 2018
In recent years, the role of big data analytics has exponentially grown and is now slowly making its way into the education industry. Several attempts are being made in this sphere in order to improve the quality of education being provided to students and while many collaborations have been carried out before, automated scoring of answers has been ...
Akash Nagaraj   +2 more
openaire   +2 more sources

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