Results 61 to 70 of about 99,927 (260)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Automated Graphic Divergent Thinking Assessment: A Multimodal Machine Learning Approach

Journal of Intelligence
This study proposes a multimodal deep learning model for automated scoring of image-based divergent thinking tests, integrating visual and semantic features to improve assessment objectivity and efficiency.
Hezhi Zhang, Hang Dong, Ying Wang, Xinyu Zhang, Fan Yu, Bailin Ren, Jianping Xu   +6 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Improving automated scoring of prosody in oral reading fluency using deep learning algorithm

Frontiers in Education
Automated assessing prosody of oral reading fluency presents challenges due to the inherent difficulty of quantifying prosody. This study proposed and evaluated an approach focusing on specific prosodic features using a deep-learning neural network.
Kuo Wang, Xin Qiao, George Sammit, Eric C. Larson, Joseph Nese, Akihito Kamata   +5 more
doaj   +1 more source

Digital assessment of mathematics: Opportunities, issues and criteria

Mesure et Évaluation en Éducation, 2018
Digital assessment of mathematics is becoming widespread, but still comes with limitations and constraints. A central question is how to design digital tests that assess mathematical knowledge in a valid way.
Paul Drijvers
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Automated Essay Scoring for Swedish.

, 2013
We present the first system developed for automated grading of high school essays written in Swedish. The system uses standard text quality indicators and is able to compare vocabulary and grammar to large reference corpora of blog posts and newspaper articles.
Östling, Robert, Smolentzov, André, Tyrefors Hinnerich, Björn, Höglin, Erik   +3 more
openaire   +2 more sources

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Real-Time Automated Answer Scoring

2018 IEEE 18th International Conference on Advanced Learning Technologies (ICALT), 2018
In recent years, the role of big data analytics has exponentially grown and is now slowly making its way into the education industry. Several attempts are being made in this sphere in order to improve the quality of education being provided to students and while many collaborations have been carried out before, automated scoring of answers has been ...
Akash Nagaraj, Mukund Sood, Gowri Srinivasa   +2 more
openaire   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source