Results 31 to 40 of about 18,507,454 (305)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Bat optimization of hybrid neural network-FOPID controllers for robust robot manipulator control
Frontiers in Robotics and AIThe position and trajectory tracking control of rigid-link robot manipulators suffers from problems such as poor accuracy, unstable performance, and response caused by unidentified loads and outside disturbances.
Bashra Kadhim Oleiwi +7 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Вестник Дагестанского государственного технического университета: Технические науки, 2019 Objectives At present, in accordance with the requirements of the guiding documents of the Federal Service for Technical and Export Control (FSTEC) of Russia, as well as international standards in the development and operation of protected automated ...
A. M. Kadnova
doaj +1 more source
Optimal amount of information determination for power system steady state estimation
Energy Reports, 2022 On the basis of literature sources analysis, the paper provides the rationale for the necessity of considering the limited digital devices capabilities when designing closed digital control systems for the complex electrical power grids.
Murad Asanov +5 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Performance Analysis of Different Machine Learning Algorithms for Predictive Maintenance
Al-Khawarizmi Engineering JournalThis research offers an extensive study of different machine learning issues for predictive maintenance applications for motor condition ranging from AC motors.
Noor A. Mohammed +3 more
doaj +1 more source