Results 51 to 60 of about 18,507,454 (305)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

A system for Indian postal automation [PDF]

Eighth International Conference on Document Analysis and Recognition (ICDAR'05), 2005
In this paper, we present a system towards Indian postal automation based on the recognition of pin-code and city name of the postal document. In the proposed system, at first, non-text blocks (postal stamp, postal seal etc.) are detected and destination address block (DAB) is identified from the document. Next, lines and words of the DAB are segmented.
Kaushik Roy 0004, Szilárd Vajda, Abdel Belaïd, U. Pal 0001, B. B. Chaudhuri 0001   +4 more
openaire   +3 more sources

Ultrasound IMT measurement on a multi-ethnic and multi-institutional database: Our review and experience using four fully automated and one semi-automated methods [PDF]

, 2012
Automated and high performance carotid intima-media thickness (IMT) measurement is gaining increasing importance in clinical practice to assess the cardiovascular risk of patients. In this paper, we compare four fully automated IMT measurement techniques
Jasjit, S., Ho SC, Saba, Luca, Suzanne C. Ho, Ledda, Giuseppe, Rajendra Acharya, U., Guang Zeng, Acharya UR, Sin Yee Stella Ho, Suri JS, U. Rajendra Acharya, Luca Saba, Ho SY, Jasjit S. Suri, Giuseppe Ledda, MEIBURGER, KRISTEN MARIKO, Andrew Nicolaides, Ledda G, Meiburger KM, Suzanne, C., Molinari, Filippo, Anil, T., Ahuja AT, Kristen, M., Zeng G, Anil T. Ahuja, Molinari F, Nicolaides A   +27 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

ON THE EFFECT OF ADAPTIVE USER INTERFACES ON RELIABILITY AND EFFICIENCY OF THE AUTOMATED SYSTEMS [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2014
In modern automated systems users often have to face the information overload problem because of ever increasing volumes of information with short time processing requirements.
Yu. O. Furtat
doaj  

AUTOMATION CONTROL SYSTEM OF TECHNICAL CONDITION OF GAS TURBINE ENGINE COMPRESSOR

Авіаційно-космічна техніка та технологія, 2019
The article is devoted to one of the approaches to the construction of an automated system for solving the problems of diagnostics and monitoring of the flow duct of aircraft gas turbine engines and gas turbine plants.
Микола Сергійович Кулик, Володимир Вікторович Козлов, Лариса Георгіївна Волянська   +2 more
doaj   +1 more source

Personalised correction, feedback, and guidance in an automated tutoring system for skills training [PDF]

, 2008
In addition to knowledge, in various domains skills are equally important. Active learning and training are effective forms of education. We present an automated skills training system for a database programming environment that promotes procedural ...
Kenny, Claire, Pahl, Claus
core   +2 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

ALGORITHMIC SUPPORT OF INFORMATION PROCESSING IN THE VOLUNTEER CENTER MANAGEMENT SYSTEM

Современная наука и инновации, 2022
The results of the development of algorithmic support for the project "Automated Information System of the Volunteer Center" are presented, the purpose of which is to obtain a multifunctional tool for planning and distribution of human and time resources,
E. A. Ilina, Y. V. Kocherzhinskaya, N. A. Dyakonov, V. A. Dyatlovskiy   +3 more
doaj