Results 61 to 70 of about 850,119 (312)

AUTOMATION CONTROL SYSTEM OF TECHNICAL CONDITION OF GAS TURBINE ENGINE COMPRESSOR

Авіаційно-космічна техніка та технологія, 2019
The article is devoted to one of the approaches to the construction of an automated system for solving the problems of diagnostics and monitoring of the flow duct of aircraft gas turbine engines and gas turbine plants.
Микола Сергійович Кулик, Володимир Вікторович Козлов, Лариса Георгіївна Волянська   +2 more
doaj   +1 more source

On building automation system security

High-Confidence Computing
Building Automation Systems (BASs) are seeing increased usage in modern society due to the plethora of benefits they provide such as automation for climate control, HVAC systems, entry systems, and lighting controls. Many BASs in use are outdated and suffer from numerous vulnerabilities that stem from the design of the underlying BAS protocol.
Christopher Morales-Gonzalez, Matthew Harper, Michael Cash, Lan Luo, Zhen Ling 0001, Qun Zhou Sun, Xinwen Fu   +6 more
openaire   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Automated segmentation of tissue images for computerized IHC analysis [PDF]

, 2010
This paper presents two automated methods for the segmentation ofimmunohistochemical tissue images that overcome the limitations of themanual approach aswell as of the existing computerized techniques.
Enrico Macii, Elisa Ficarra, Santa Di Cataldo, Ficarra, Elisa, Acquaviva, Andrea, Di Cataldo, Santa, Macii, Enrico   +6 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

ALGORITHMIC SUPPORT OF INFORMATION PROCESSING IN THE VOLUNTEER CENTER MANAGEMENT SYSTEM

Современная наука и инновации, 2022
The results of the development of algorithmic support for the project "Automated Information System of the Volunteer Center" are presented, the purpose of which is to obtain a multifunctional tool for planning and distribution of human and time resources,
E. A. Ilina, Y. V. Kocherzhinskaya, N. A. Dyakonov, V. A. Dyatlovskiy   +3 more
doaj  

Fully Automated Microsystem for Unmediated Electrochemical Characterization, Visualization and Monitoring of Bacteria on Solid Media; E. coli K-12: A Case Study

Biosensors, 2019
In this paper, we present a non-fluidic microsystem for the simultaneous visualization and electrochemical evaluation of confined, growing bacteria on solid media.
Cesar A. Hernandez, Valerio Beni, Johann F. Osma   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Characterization of security defects and analysis of vulnerability criticality in software for automated systems of internal affairs bodies

Вестник Дагестанского государственного технического университета: Технические науки
Objective. The purpose of the study is to theoretically analyze security defects and study the criticality of vulnerabilities in software used in modern automated systems of internal affairs agencies.Method.
I. G. Drovnikova, A. D. Popova
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source