Results 71 to 80 of about 279,436 (276)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Virtual reality simulation for the optimization of endovascular procedures : current perspectives [PDF]
, 2015 Endovascular technologies are rapidly evolving, often - requiring coordination and cooperation between clinicians and technicians from diverse specialties.
Cheshire, Nicholas JW +3 more
core +2 more sources
A reinforcement learning agent for head and neck intensity-modulated radiation therapy
Frontiers in PhysicsHead and neck (HN) cancers pose a difficult problem in the planning of intensity-modulated radiation therapy (IMRT) treatment. The primary tumor can be large and asymmetrical, and multiple organs at risk (OARs) with varying dose-sparing goals lie close ...
Hunter Stephens +5 more
doaj +1 more source
JMIR Medical Informatics, 2021 BackgroundThough shock wave lithotripsy (SWL) has developed to be one of the most common treatment approaches for nephrolithiasis in recent decades, its treatment planning is often a trial-and-error process based on physicians’ subjective judgement ...
Chen, Zhipeng +3 more
doaj +1 more source
Learning Effective Changes for Software Projects
, 2017 The primary motivation of much of software analytics is decision making. How to make these decisions? Should one make decisions based on lessons that arise from within a particular project?
Krishna, Rahul
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Development and evaluation of radiotherapy deep learning dose prediction models for breast cancer
Physics and Imaging in Radiation Oncology, 2021 Background and purpose: Treatment planning of radiotherapy is a time-consuming and planner dependent process that can be automated by dose prediction models.
Nienke Bakx +5 more
doaj +1 more source
KEMNAD: A Knowledge Engineering Methodology for Negotiating Agent Development [PDF]
, 2012 Automated negotiation is widely applied in various domains. However, the development of such systems is a complex knowledge and software engineering task. So, a methodology there will be helpful.
He, Minghua +5 more
core +3 more sources