Results 71 to 80 of about 2,190,498 (300)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A Variable Structure Control Scheme Proposal for the Tokamak à Configuration Variable

Complexity, 2019
Fusion power is the most significant prospects in the long-term future of energy in the sense that it composes a potentially clean, cheap, and unlimited power source that would substitute the widespread traditional nonrenewable energies, reducing the ...
Aitor Marco, Aitor J. Garrido, Stefano Coda, Izaskun Garrido, TCV Team   +4 more
doaj   +1 more source

AScall – Automatic Allele-Specific qPCR Analysis

Frontiers in Bioengineering and Biotechnology, 2020
Minor histocompatibility antigens (MiHA) are critical elements for the immune response after allogeneic hematopoietic stem cell transplantation. They may cause both beneficial and detrimental effects in forms of graft-versus-tumor and graft-versus-host ...
Konstantin Blagodatskikh, Dmitrii Romaniuk, Dmitry Malko   +2 more
doaj   +1 more source

Automatic Analysis of Facial Expressions Based on Deep Covariance Trajectories [PDF]

, 2019
In this paper, we propose a new approach for facial expression recognition using deep covariance descriptors. The solution is based on the idea of encoding local and global Deep Convolutional Neural Network (DCNN) features extracted from still images, in
Ballihi, Lahoucine, Berretti, Stefano, Daoudi, Mohamed, Kacem, Anis, Otberdout, Naima   +4 more
core   +5 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

TAGGING, MORPHOLOGICAL DICTIONARY IN ELECTRONIC FORM, LEMMATIZATION AND NORMALIZATION OF TEXTS

Издател, 2020
The paper deals with the process of automatic morphological analysis. The issues of morphology and the operations in it are briefly discussed. The morphological dictionary in electronic form is discussed and also the process of automatic morphological ...
Elisaveta Balabanova
doaj   +1 more source

Making formal verification amenable to real-time UML practitioners [PDF]

, 2009
TTool, a real-time UML toolkit, offers user-friendly interfaces to formal verification techniques such as reachability analysis, observer-based analysis and automatic generation of traceability matrices.
Apvrille, Ludovic, Saqui-Sannes, Pierre de   +1 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A survey on mouth modeling and analysis for Sign Language recognition [PDF]

, 2015
© 2015 IEEE.Around 70 million Deaf worldwide use Sign Languages (SLs) as their native languages. At the same time, they have limited reading/writing skills in the spoken language.
Antonakos, E, Roussos, A, Zafeiriou, S
core   +2 more sources