Results 111 to 120 of about 6,422,664 (364)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Analyse de la production de voyelles anglaises par des apprenants francophones, l’acquisition du contraste /ɪ/–/iː/ à la lumière des k-NN

open access: yesAnglophonia, 2019
Can methods of supervised learning help to evaluate the degree of acquisition of a contrast in a second language? This article addresses the issue of assessing the realizations of /ɪ/ and /iː/ by French learners of English in spontaneous conversations by
Adrien Méli, Nicolas Ballier
doaj   +1 more source

Automatic object detection based on adaptive background subtraction using symmetric alpha stable distribution [PDF]

open access: yes, 2008
Automatic detection of objects is critical to video tracking systems. One of the simplest techniques for detection is background subtraction (BS). BS refers to the process of segmenting moving regions from image sequences.
Bhaskar, H., Maskell, S., Mihaylova, L.
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Automatically Detected Pecking Activity in Group-Housed Turkeys

open access: yesAnimals, 2020
In search for an early warning system for cannibalism, in this study a newly developed automatic pecking activity detection system was validated and used to investigate how pecking activity changes over the rearing phase and before cannibalistic ...
Jennifer J. Gonzalez   +2 more
doaj   +1 more source

Automatic Detection of Translation Direction

open access: yesProceedings - Natural Language Processing in a Deep Learning World, 2019
Parallel corpora are crucial resources for NLP applications, most notably for machine translation. The direction of the (human) translation of parallel corpora has been shown to have significant implications for the quality of statistical machine translation systems that are trained with such corpora.
Ilia Sominsky, Shuly Wintner
openaire   +1 more source

Multi-spectral and digital elevation model information fusion for automatic 3d change detection

open access: yes, 2011
Various 2D and 3D change detection techniques have been developed in the literature to monitor changes inside urban areas. Nevertheless, most of theses techniques require the interaction of the user either to input data, set parameters, or to train ...
Chaabouni-Chouayakh, Houda   +2 more
core  

Hybrid image representation methods for automatic image annotation: a survey [PDF]

open access: yes, 2012
In most automatic image annotation systems, images are represented with low level features using either global methods or local methods. In global methods, the entire image is used as a unit.
Oukid, Saliha   +7 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Adaptive Quasi-Unsupervised Detection of Smoke Plume by LiDAR

open access: yesSensors, 2020
The early detection of fire is one of the possible applications of LiDAR techniques. The smoke generated by a fire is mainly compounded of CO2, H2O, particulate, and other combustion products, which involve the local variation of the scattering of the ...
Riccardo Rossi   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy