Results 51 to 60 of about 29,443 (297)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Heuristic Evaluation for Serious Immersive Games and M-instruction [PDF]

, 2016
© Springer International Publishing Switzerland 2016. Two fast growing areas for technology-enhanced learning are serious games and mobile instruction (M-instruction or M-Learning). Serious games are ones that are meant to be more than just entertainment.
Aljaber, Tareq, Brayshaw, Mike, Gordon, Neil   +2 more
core   +1 more source

Date fruit detection dataset for automatic harvesting

Data in Brief
Date fruit is one of the most beneficial and delicious fruits in the world through its nutritional value, it's a rich source of sugar, Protein, Manganese, Fibers, and many other vitamins, on the other hand, date production in the world reached up to 9.45 million tons, one palm tree can produce dates for 40 to 50 years which makes date production one of
Yousra Zarouit, HASSAN ZEKKOURI, Mohamed Ouhda, Brahim Aksasse   +3 more
openaire   +3 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Integration of a Mobile Laser Scanning System with a Forest Harvester for Accurate Localization and Tree Stem Measurements

Remote Sensing
Automating forest machines to optimize the forest value chain requires the ability to map the surroundings of the machine and to conduct accurate measurements of nearby trees. In the near-to-medium term, integrating a forest harvester with a mobile laser
Tamás Faitli, Eric Hyyppä, Heikki Hyyti, Teemu Hakala, Harri Kaartinen, Antero Kukko, Jesse Muhojoki, Juha Hyyppä   +7 more
doaj   +1 more source

Research on the Measurement Method of Feeding Rate in Silage Harvester Based on Components Power Data

Agriculture, 2023
For existing problems, such as the complex interactions between a crop and a machine, the measuring difficulty and the limited measurement precision of the feeding quantity within the corn silage harvester, a method of feeding rate measurement based on ...
Fengzhu Wang, Jizhong Wang, Yuxi Ji, Bo Zhao, Yangchun Liu, Hanlu Jiang, Wenhua Mao   +6 more
doaj   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source

Prediction of stem attributes by combining airborne laser scanning and measurements from harvesters

Silva Fennica, 2012
In this study, a new method was validated for the first time that predicts stem attributes for a forest area without any manual measurements of tree stems by combining harvester measurements and Airborne Laser Scanning (ALS) data.
Holmgren, Johan, Barth, Andreas, Larsson, Henrik, Olsson, Håkan   +3 more
doaj   +1 more source

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

Advanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal, Michael M. Becker, Sarah C. L. Fischer   +2 more
wiley   +1 more source