Results 81 to 90 of about 144,803 (288)

Deep learning driven multi-scale spatiotemporal fusion dance spectrum generation network: A method based on human pose fusion

Alexandria Engineering Journal
With the integration of dance art and computer technology, automatic dance score generation has become a new research direction in computer vision and machine learning, but generating the corresponding Laban symbols by capturing the skeletal key points ...
Doudou Sun, Gang Wang
doaj   +1 more source

Automatic selection of sequence transformations [PDF]

Mathematics of Computation, 1981
Some methods of automatic selection of sequence transformations for accelerating the convergence of sequences are presented. Two theorems show the efficiency of these methods. This is confirmed by numerical experiments.
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

BrEPS 2.0: Optimization of sequence pattern prediction for enzyme annotation. [PDF]

PLoS ONE, 2017
The prediction of gene functions is crucial for a large number of different life science areas. Faster high throughput sequencing techniques generate more and larger datasets.
Christian-Alexander Dudek, Henning Dannheim, Dietmar Schomburg   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

A patch-based method for repetitive and transient event detection in fluorescence imaging. [PDF]

PLoS ONE, 2010
Automatic detection and characterization of molecular behavior in large data sets obtained by fast imaging in advanced light microscopy become key issues to decipher the dynamic architectures and their coordination in the living cell.
Jérôme Boulanger, Alexandre Gidon, Charles Kervran, Jean Salamero   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Arithmetical subword complexity of automatic sequences

, 2023
14 pages, comments welcomeInternational audienceWe fully classify automatic sequences a over a finite alphabet Ω with the property that each word over Ω appears is a along an arithmetic progression.
Konieczny, Jakub, Müllner, Clemens
core   +2 more sources

Sequencing and identification of expressed Schistosoma mansoni genes by random selection of cDNA clones from a directional library

Memorias do Instituto Oswaldo Cruz, 1995
We have initiated a gene discovery program in Schistosoma mansoni based on the technique of Expressed Sequence Tags (ESTs), i.e. partial sequences of cDNAs obtained from single passes in automatic DNA sequencers.
Glória R. Franco, Andrew J. G. Simpson, Sérgio D. J. Pena   +2 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source