Results 61 to 70 of about 144,803 (288)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Automatic Album Sequencing

CoRR
Album sequencing is a critical part of the album production process. Recently, a data-driven approach was proposed that sequences general collections of independent media by extracting the narrative essence of the items in the collections. While this approach implies an album sequencing technique, it is not widely accessible to a less technical ...
Vincent Herrmann, Dylan R. Ashley, Jürgen Schmidhuber   +2 more
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Automatic Playlist Sequencing And Transitions. [PDF]

, 2017
[TODO] Add abstract here.
Rachel M. Bittner, Minwei Gu, Gandalf Hernandez, Eric J. Humphrey, Tristan Jehan, Hunter McCurry, Nicola Montecchio   +6 more
openaire   +1 more source

Integrality and the Laurent phenomenon for Somos 4 and Somos 5 sequences [PDF]

, 2008
Somos 4 sequences are a family of sequences defined by a fourth-order quadratic recurrence relation with constant coefficients. For particular choices of the coefficients and the four initial data, such recurrences can yield sequences of integers.
Swart, Christine, Hone, Andrew N.W.
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

DPCfam: Unsupervised protein family classification by Density Peak Clustering of large sequence datasets.

PLoS Computational Biology, 2022
Proteins that are known only at a sequence level outnumber those with an experimental characterization by orders of magnitude. Classifying protein regions (domains) into homologous families can generate testable functional hypotheses for yet unannotated ...
Elena Tea Russo, Federico Barone, Alex Bateman, Stefano Cozzini, Marco Punta, Alessandro Laio   +5 more
doaj   +1 more source

Myocardial Segmentation of Cardiac MRI Sequences With Temporal Consistency for Coronary Artery Disease Diagnosis

Frontiers in Cardiovascular Medicine, 2022
Coronary artery disease (CAD) is the most common cause of death globally, and its diagnosis is usually based on manual myocardial (MYO) segmentation of MRI sequences.
Yutian Chen, Yutian Chen, Yutian Chen, Wen Xie, Wen Xie, Jiawei Zhang, Jiawei Zhang, Jiawei Zhang, Jiawei Zhang, Hailong Qiu, Hailong Qiu, Dewen Zeng, Yiyu Shi, Haiyun Yuan, Haiyun Yuan, Jian Zhuang, Jian Zhuang, Qianjun Jia, Qianjun Jia, Yanchun Zhang, Yuhao Dong, Yuhao Dong, Yuhao Dong, Meiping Huang, Meiping Huang, Meiping Huang, Xiaowei Xu, Xiaowei Xu   +27 more
doaj   +1 more source

Optimal Description of Automatic Paperfolding Sequences

, 1997
The class of 2-automatic paperfolding sequences corresponds to the class of ultimately periodic sequences of unfolding instructions. We first show that a paper-folding sequence is automatic iff it is 2-automatic.
Cerny,Anton, Cerny, Anton
core   +1 more source

Finding automatic sequences with few correlations

, 2022
International audienceAlthough automatic sequences are very simple algorithmically, some of them have pseudo-random properties. In particular, some automatic sequences such as the Golay–Shapiro sequence are known to be 2-uncorrelated, meaning that they ...
Marcovici, Irène, Jugé, Vincent
core   +1 more source