Results 71 to 80 of about 824,134 (332)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Defogging Algorithm Based on Polarization Characteristics and Atmospheric Transmission Model

Sensors, 2022
We propose a polarized image defogging algorithm according to the sky segmentation results and transmission map optimization. Firstly, we propose a joint sky segmentation method based on scene polarization information, gradient information and light ...
Feng Ling, Yan Zhang, Zhiguang Shi, Jinghua Zhang, Yu Zhang, Yi Zhang   +5 more
doaj   +1 more source

Fusing Deep Learning and Sparse Coding for SAR ATR [PDF]

, 2018
We propose a multimodal and multidiscipline data fusion strategy appropriate for automatic target recognition (ATR) on synthetic aperture radar imagery. Our architecture fuses a proposed clustered version of the AlexNet convolutional neural network with ...
Aouf, N., Kechagias-Stamatis, O.
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

An Infrared Maritime Small Target Detection Algorithm Based on Semantic, Detail, and Edge Multidimensional Information Fusion

Remote Sensing, 2023
The infrared small target detection technology has a wide range of applications in maritime defense warning and maritime border reconnaissance, especially in the maritime and sky scenes for detecting potential terrorist attacks and monitoring maritime ...
Jiping Yao, Shanzhu Xiao, Qiuqun Deng, Gongjian Wen, Huamin Tao, Jinming Du   +5 more
doaj   +1 more source

A Hybrid Neural Network Framework and Application to Radar Automatic Target Recognition

, 2018
Deep neural networks (DNNs) have found applications in diverse signal processing (SP) problems. Most efforts either directly adopt the DNN as a black-box approach to perform certain SP tasks without taking into account of any known properties of the ...
Chen, Xiang, Tian, Zhi, Zhang, Zhe
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Improving YOLOv7-Tiny for Infrared and Visible Light Image Object Detection on Drones

Remote Sensing, 2023
To address the phenomenon of many small and hard-to-detect objects in drone images, this study proposes an improved algorithm based on the YOLOv7-tiny model.
Shuming Hu, Fei Zhao, Huanzhang Lu, Yingjie Deng, Jinming Du, Xinglin Shen   +5 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Primitive-based 3D Abstraction Method for Spacecraft ISAR Images

Leida xuebao
Inverse Synthetic Aperture Radar (ISAR) images of spacecraft are composed of discrete scatterers that exhibit weak texture, high dynamics, and discontinuity.
Canyu WANG, Libing JIANG, Xiaoyuan REN, Zhuang WANG   +3 more
doaj   +1 more source