Results 31 to 40 of about 37,891 (240)

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi   +9 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Comparison and evaluation of job selection dispatching rules for integrated scheduling of multi-load automatic guided vehicles serving in variable sized flexible manufacturing system layouts: A simulation study

open access: yesManagement Science Letters, 2018
This paper compares and evaluates the performance of five different conventional job selection dis-patching rules for scheduling of multi-load automatic guided vehicles (AGVs) serving for material handling operations in variable sized flexible manufacturing system (FMS) layout.
S. Angra, A. K. Chanda, V. K. Chawla
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A Lightweight, Simple-Structure, Low-Cost and Compliant Twisted String Actuator Featuring Continuously Variable Transmission

open access: yesActuators
Twisted string actuators, which are an emerging artificial muscle, efficiently convert rotary motor motion into linear load movement, with advantages like high transmission ratio, compliance, simple structure, and long-distance power transmission ...
Chanchan Xu   +4 more
doaj   +1 more source

Shock Absorbers Multi-Modeling and Suspension Optimization [PDF]

open access: yesJournal of Electrical and Electronics Engineering, 2013
The standard dampers used by more 90% of vehicles have damping coefficients constant along stroke, so they can’t solve simultaneous all of them, situation solving practically using a relative dampingcoefficient able to made compromise between them.
LUPU Ciprian   +3 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Load sensitive control characteristics of a novel two-dimensional pulse width modulated variable mechanism

open access: yesAdvances in Mechanical Engineering
Load sensing technology is a typical hydraulic technology that automatically meets load requirements by adjusting the pressure and flow at the pump outlet.
Wu Jian, Ruan Jian, Ren Yan
doaj   +1 more source

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