Results 41 to 50 of about 37,891 (240)
Lighting Control System Based on the RTP of Smart Grid in WSN
International Journal of Distributed Sensor Networks, 2015 This paper proposes a lighting control system based on RTP to save lighting energy cost by utilizing daylight while maintaining target luminance suited to the purpose.
Kyoung-Mi Im, Jae-Hyun Lim
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
METHOD FOR REDUCTIVE PRUNING OF NEURAL NETWORKS AND ITS APPLICATIONS
Компютерні системи та інформаційні технології, 2022 Trained neural networks usually contain redundant neurons that do not affect or degrade the quality of target identification. The redundancy of models possesses an excessive load on computational resources, leading to high electricity consumption ...
Oleksandr Gurbych, Maksym Prymachenko
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Input-parallel–output-series control strategy for three-level medium-voltage DC grid-type converter
The Journal of Engineering, 2019 A control topology input-parallel–output-series converter system is investigated, which is suitable for high-voltage and high-output power applications.
Faisal Mehmood Shah +6 more
doaj +1 more source
Automatic current-voltage characteristic measurement using transistors as variable load
Қарағанды университетінің хабаршысы. Физика сериясы, 2015 The article describes a method for measuring current-voltage characteristics using transistors as a variable load. Suggested system is part of an automated quality control complex for space applications solar panels. As a part of the description of the system its integral parts are described, both hardware and software. Several examples of calculations
Zh.S. Bekturhanov, S.V. Kussaikin
openaire +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source