Results 51 to 60 of about 37,927 (278)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Development of measurement-based load models for the dynamic simulation of distribution grids

open access: yes, 2017
The advent of new types of loads, such as power electronics and the increased penetration of low-inertia motors in the existing distribution grids alter the dynamic behavior of conventional power systems. Therefore, more accurate dynamic, aggregate, load
Guillo-Sansano, Efren   +6 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

An Intelligent and Automated Approach for Smart Minimarkets

open access: yesInternational Journal of Computational Intelligence Systems, 2020
This paper presents the design and implementation of a smart and safe minimarket prototype for deployment in busy smart cities to mitigate the overhead of shopping experience.
Talal A. Edwan   +4 more
doaj   +2 more sources

Consensus between pipelines in structural brain networks. [PDF]

open access: yes, 2014
Structural brain networks may be reconstructed from diffusion MRI tractography data and have great potential to further our understanding of the topological organisation of brain structure in health and disease.
Dayan, M   +48 more
core   +1 more source

Fuzzy C-means clustering based on micro-spatial analysis for electricity load profile characterization

open access: yes, 2023
As the rising of electricity demand, electricity load profile characterization (ELPC) is the integral aspect in planning, operating system, and distribution network development.
Jasrul Jamani Jamian   +9 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Input-parallel–output-series control strategy for three-level medium-voltage DC grid-type converter

open access: yesThe Journal of Engineering, 2019
A control topology input-parallel–output-series converter system is investigated, which is suitable for high-voltage and high-output power applications.
Faisal Mehmood Shah   +6 more
doaj   +1 more source

Automatic current-voltage characteristic measurement using transistors as variable load

open access: yesҚарағанды университетінің хабаршысы. Физика сериясы, 2015
The article describes a method for measuring current-voltage characteristics using transistors as a variable load. Suggested system is part of an automated quality control complex for space applications solar panels. As a part of the description of the system its integral parts are described, both hardware and software. Several examples of calculations
Zh.S. Bekturhanov, S.V. Kussaikin
openaire   +1 more source

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