Results 71 to 80 of about 342,046 (278)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Index to NASA Tech Briefs, January - June 1966 [PDF]
Index to NASA technological innovations for January-June ...
core +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
EET Senior Design Project - IMS Dynamic Display [PDF]
Indiana University Purdue University IndianapolisThe Indianapolis Motor Speedway Museum has a display transmission that is still actively used in IndyCar today. The museum wants to incorporate this transmission into an interactive display, so guests of
Boggess, John, Elkins, Michael
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Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
High speed cylindrical roller bearing analysis. SKF computer program CYBEAN. Volume 2: User's manual [PDF]
CYBEAN (CYlindrical BEaring ANalysis) was created to detail radially loaded, aligned and misaligned cylindrical roller bearing performance under a variety of operating conditions.
Dyba, G. J., Kleckner, R. J.
core +1 more source
Index to nasa tech briefs, issue number 2 [PDF]
Annotated bibliography on technological innovations in NASA space ...
core +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Frontotemporal dementia (FTD) is a heterogeneous group of neurodegenerative disorders with both sporadic and genetic forms. Mutations in the progranulin gene (GRN) are a common cause of genetic FTD, causing either a behavioural presentation or, less ...
Carole H. Sudre +40 more
doaj +1 more source
Development of a Novel MultiBody Mechatronic Model for Five-Axis CNC Machine Tool [PDF]
The paper presents the development of a mechatronic hybrid model for Geiss five-axis CNC machine tool using MultiBody-System (MBS) approach. The motion control systems comprising electrical and mechanical elements are analyzed and modeled.
Papananias, M. +2 more
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