Results 71 to 80 of about 342,046 (278)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Index to NASA Tech Briefs, January - June 1966 [PDF]

open access: yes, 1966
Index to NASA technological innovations for January-June ...

core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

EET Senior Design Project - IMS Dynamic Display [PDF]

open access: yes, 2019
Indiana University Purdue University IndianapolisThe Indianapolis Motor Speedway Museum has a display transmission that is still actively used in IndyCar today. The museum wants to incorporate this transmission into an interactive display, so guests of
Boggess, John, Elkins, Michael
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

High speed cylindrical roller bearing analysis. SKF computer program CYBEAN. Volume 2: User's manual [PDF]

open access: yes
CYBEAN (CYlindrical BEaring ANalysis) was created to detail radially loaded, aligned and misaligned cylindrical roller bearing performance under a variety of operating conditions.
Dyba, G. J., Kleckner, R. J.
core   +1 more source

Index to nasa tech briefs, issue number 2 [PDF]

open access: yes, 1965
Annotated bibliography on technological innovations in NASA space ...

core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

White matter hyperintensities in progranulin-associated frontotemporal dementia: A longitudinal GENFI study

open access: yesNeuroImage: Clinical, 2019
Frontotemporal dementia (FTD) is a heterogeneous group of neurodegenerative disorders with both sporadic and genetic forms. Mutations in the progranulin gene (GRN) are a common cause of genetic FTD, causing either a behavioural presentation or, less ...
Carole H. Sudre   +40 more
doaj   +1 more source

Development of a Novel MultiBody Mechatronic Model for Five-Axis CNC Machine Tool [PDF]

open access: yes, 2015
The paper presents the development of a mechatronic hybrid model for Geiss five-axis CNC machine tool using MultiBody-System (MBS) approach. The motion control systems comprising electrical and mechanical elements are analyzed and modeled.
Papananias, M.   +2 more
core  

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