Results 61 to 70 of about 342,046 (278)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Prognostic Reasoner based adaptive power management system for a more electric aircraft [PDF]
, 2016 This research work presents a novel approach that addresses the concept of an adaptive power management system design and development framed in the Prognostics and Health Monitoring(PHM) perspective of an Electrical power Generation and distribution ...
Alghassi, Alireza +3 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Jixie chuandong, 2009 Traction drives possesses some inherent advantages when compared with gears. Traction drive can be classified into two major categories:fixed ratio transmission （FRT） and continuous variable speed transmission （CVT）.
陈德生, 潘荣荣
doaj
Provision of Ancillary Services with Variable Speed Wind Turbines [PDF]
, 2014 In recent years, the amount of wind turbines in the power system has increased tremendously. As the current wind turbines do not participate in the provision of ancillary services such as frequency control and voltage control, this may compromise the ...
De Kooning, Jeroen +4 more
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Automatic code generation for ATLAS communications drivers [PDF]
, 1999 ATLAS is a software development platform created in our Department. Among other benefits, it provides support to easily distribute applications over a network.
Fairén González, Marta +2 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Effects of control laws and relaxed static stability on vertical ride quality of flexible aircraft [PDF]
State variable techniques are utilized to generate the RMS vertical load factors for the B-52H and B-1 bombers at low level, mission critical, cruise conditions.
Hinsdale, A. J. +3 more
core +1 more source