Results 61 to 70 of about 724,055 (291)

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Significant Microvascular Abnormalities Present in Autonomic Nervous System Dysfunction: Results of a Cross-Sectional Study

Biomedicines
Purpose: The prevalence and phenotype of capillaroscopic abnormalities in patients with autonomic nervous system dysfunction have not yet been investigated. Multiorgan involvement in dysautonomia entails abnormal vasoreactivity.
Sehreen Mumtaz, Karissa Arca, Vikas Majithia, William Cheshire, David Hodge, Florentina Berianu   +5 more
doaj   +1 more source

Autonomic Dysfunction in α-Synucleinopathies [PDF]

Frontiers in Neurology, 2019
اعتلالات ألفا المزامنة هي مجموعة من الأمراض التنكسية العصبية التي تتميز بتراكم غير طبيعي من ألفا المزامنة غير القابلة للذوبان في الخلايا العصبية والخلايا الدبقية، بما في ذلك مرض باركنسون (PD)، والخرف مع أجسام ليوي (DLB) وضمور الجهاز المتعدد (MSA). على الرغم من اختلافها في الانتشار وأنماط الأعراض والشدة بين الاضطرابات، إلا أن جميع اعتلالات ألفا المزامنة
José Javier Mendoza-Velásquez, José Javier Mendoza-Velásquez, Juan Francisco Flores-Vázquez, Juan Francisco Flores-Vázquez, Evalinda Barrón-Velázquez, Ana Luisa Sosa-Ortiz, Ben-Min Woo Illigens, Ben-Min Woo Illigens, Timo Siepmann, Timo Siepmann   +9 more
openaire   +3 more sources

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Autonomic Dysfunction In Preschool Children

Interdisciplinary Approaches to Medicine, 2020
High prevalence of autonomic dysfunction syndrome in schoolchildren was found, the specifics of its clinical presentation with identification of the most salient symptoms are given. The purpose of the work was to find the occurrence of NS (nervous system) functional disorders in various age groups, with gender differences noted, among schoolchildren of
R.B. Issayeva, G.T. Tashenova, Laimute Vaideliene, A.Zh. Ahenbekova, R.Z. Boranbaeva   +4 more
openaire   +4 more sources

Autonomic dysfunction and sleep disorders

, 2017
Autonomic dysfunctions are frequently associated with sleep disorders, as the autonomic nervous system and sleep are closely related from anatomical, physiological, and neurochemical points of view.
Pietro Cortelli, Giovanna Calandra-Buonaura   +1 more
core   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Clinical features of autonomic dysfunction in children with anti-N-methyl-D aspartic receptor encephalitis

Italian Journal of Pediatrics
Background Anti-N-methyl-D-aspartic receptor encephalitis (Anti-NMDAR encephalitis) is the most prevalent form of autoimmune encephalitis in pediatric patients.
Dongqing Li, Jing Sun, Guannan Li, Shuo Miao, Jian Yang, Jianzhao Zhang   +5 more
doaj   +1 more source

Autonomic dysfunction score.

, 2015
Number of cases with 0, 1, 2, and 3 points in the exercise treadmill test autonomic dysfunction score in controls and hemodialysis patients. Parameters that composed the autonomic dysfunction score were: chronotropic index, heart rate recovery in 1st min
Maria Angela M. Q. Carreira (749554), André B. Nogueira (749555), Marcio G. Kiuchi (749557), Jocemir R. Lugon (749561), Jorge P. S. Matos (749560), Rodrigo R. Rodrigues (749559), Felipe M. Pena (749556), Ronaldo C. Rodrigues (749558)   +7 more
core   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source