Results 61 to 70 of about 2,841 (249)

Neuromodulation of Cardiac Ischemic Pain: Role of the Autonomic Nervous System and Vasopressin

Journal of Integrative Neuroscience
Cardiac pain is an index of cardiac ischemia that helps the detection of cardiac hypoxia and adjustment of activity in the sufferer. Drivers and thresholds of cardiac pain markedly differ in different subjects and can oscillate in the same individual ...
Ewa Szczepanska-Sadowska
doaj   +1 more source

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal, Milan Patra, Rianita Mondal, Shubhasis Haldar   +3 more
wiley   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Autonomic Nervous System and Allergic Diseases: Integrative Literature Review

, 2015
Introduction: Allergic diseases have their incidence constantly increased especially asthma, allergic rhinitis and eczema or atopic dermatitis. The causes related with the appearance of these diseases such as the environment, hereditary and others are ...
Assis, Elisangela Vilar de, Sousa, Milena Nunes Alves de, Silveira, Gylmara Bezerra de Menezes, Batista, Hermes Melo Teixeira, Feitosa, Ankilma do Nascimento Andrade, Pinheiro Bezerra, Italla Maria, Valenti, Vitor Engrácia, Isidório, Ubiraídys de Andrade, de Abreu, Luiz Carlos   +8 more
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Autonomic nervous system dysfunction and sinonasal symptoms

, 2018
Background The autonomic nervous system (ANS) richly innervates the nose and paranasal sinuses, and has a significant role in lower airway diseases, e.g., asthma. Nonetheless, its contribution to sinonasal symptoms is poorly understood. This review aimed
Janet A. Wilson FRCS (ENT), Alexander Yao MRCS (ENT), Stephen L. Ball Ph.D.   +2 more
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β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Microglia-Mediated Neuroinflammation: A Potential Target for the Treatment of Cardiovascular Diseases

Journal of Inflammation Research, 2022
Menglong Wang,1– 3,* Wei Pan,1– 3,* Yao Xu,1– 3,* Jishou Zhang,1– 3 Jun Wan,1– 3 Hong Jiang1– 3 1Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, 430060, People’s Republic of China; 2Cardiovascular Research Institute ...
Wang M, Pan W, Xu Y, Zhang J, Wan J, Jiang H   +5 more
doaj  

Cardiorespiratory and autonomic-nervous-system functioning of drug abusers treated by Zen meditation

Journal of Traditional and Complementary Medicine, 2019
Addicted drugs like nicotine affect autonomic nervous system that results in arrhythmia and other cardiovascular diseases. Notable effects of Zen meditation on autonomic nervous system have been reported during the past decade. Holistic Detox Association
Pei-Chen Lo, Ping-Hsien Tsai, Hui-Jane Kang, Wu Jue Miao Tian   +3 more
doaj   +1 more source

Simulation of Cardiovascular System Diseases by Including the Autonomic Nervous System in a Minimal Model [PDF]

, 2007
Diagnosing cardiovascular system (CVS) diseases from clinically measured data is difficult, due to the complexity of the hemodynamic and autonomic nervous system (ANS) interactions.
Andreassen, Steen, Jensen, Per L., Chase, J. Geoffrey, Smith, Bram Wallace, Rees, Stephen Edward, Smith, B.W., Shaw, Geoff, Chase, Geoff, Shaw, Geoffrey M., Rees, S.E., Andreassen, S., Jensen, P.L.   +11 more
core   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source