Results 81 to 90 of about 20,075,313 (301)
Advanced Science, EarlyView.. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li +15 more
wiley +1 more source
The autonomic nervous system and renal physiology
, 2013 John A D'Elia,1,2 Larry A Weinrauch1,2 1Joslin Diabetes Center, Beth Israel Deaconess Medical Center, Boston, MA, USA; 2Department of Medicine, Harvard Medical School, Boston, MA, USA Abstract: Research in resistant hypertension has again focused on ...
Weinrauch LA, D'Elia JA
core
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Physiological approach to neuropsychiatric diseases; role of autonomic nervous system and melatonin
Psychiatry and Clinical Psychopharmacology, 2021 Adaptation is a continuous process between the genes of a particular species and its environment. Although a couple of weeks are long enough to adapt to some environmental changes, sometimes several generations are needed to adapt.
Ahmet Korkmaz +3 more
doaj
Advanced Science, EarlyView.Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang +6 more
wiley +1 more source
CURRENT GUIDELINES FOR DIAGNOSIS AND TREATMENT OF VEGETATIVE DYSTONIA IN CHILDREN AND ADOLESCENTS
Медицинский совет, 2016 Disorders of the autonomic nervous system represent a relevant problem in the modern pediatric and adolescent health care due to high prevalence, polymorphism of clinical manifestations, and a negative impact on the quality of life of children and ...
I. N. Zakharova +2 more
doaj +1 more source
Autonomic nervous system involvement in a new CMT2B family.
, 2012 We describe the first Italian family affected by CMT2B carrying a Val162Met substitution in the RAB7 gene. The clinical and electrophysiological features of our family are similar to those of previously reported families with RAB7 mutations, also for the
Nolano M +18 more
core +1 more source
Advanced Science, EarlyView.Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang +3 more
wiley +1 more source
Insights into the background of autonomic medicine
Revista Portuguesa de Cardiologia, 2017 Knowledge of the physiology underlying the autonomic nervous system is pivotal for understanding autonomic dysfunction in clinical practice. Autonomic dysfunction may result from primary modifications of the autonomic nervous system or be secondary to a ...
Sérgio Laranjo +3 more
doaj +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
Advanced Science, EarlyView.We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source