Perspectives of glycemic variability in diabetic neuropathy: a comprehensive review
Zhang et al. describe metrics for evaluating glycaemic variability (GV) in clinical practice and summarize the role and related mechanisms of GV in diabetic neuropathy, including cardiovascular autonomic neuropathy, diabetic peripheral neuropathy and ...
Xiaochun Zhang+3 more
doaj +1 more source
Cardiac autonomic neuropathy in patients with diabetes mellitus.
Cardiac autonomic neuropathy (CAN) is an often overlooked and common complication of diabetes mellitus. CAN is associated with increased cardiovascular morbidity and mortality.
G. Dimitropoulos, A. Tahrani, M. Stevens
semanticscholar +1 more source
Cardiovascular autonomic neuropathy among non- insulin dependent diabetics patients
Background and Objective: Cardiovascular autonomic neuropathy (CAN) is the most common and important type of diabetic autonomic neuropathy. Silent myocardial infarction, respiratory failure and increased mortality are the outcomes of CAN.
Hosseini SM, Maleki AR, Bazrafshan HR
doaj
Нeart failure is common both in cardiac and noncardiac disease. We conducted a study that showed high efficacy and safety of meldonium in patients with heart failure and comorbidity.
M. E. Statsenko+4 more
doaj +1 more source
Evaluation of an AI system for the automated detection of glaucoma from stereoscopic optic disc photographs: the European Optic Disc Assessment Study [PDF]
Objectives: To evaluate the performance of a deep learning based Artificial Intelligence (AI) software for detection of glaucoma from stereoscopic optic disc photographs, and to compare this performance to the performance of a large cohort of ophthalmologists and optometrists. Methods: A retrospective study evaluating the diagnostic performance of an
arxiv
Iron role paradox in nerve degeneration and regeneration [PDF]
Iron accumulates in the neural tissue during peripheral nerve degeneration. Some studies have already been suggested that iron facilitates Wallerian degeneration (WD) events such as Schwann cell de-differentiation. On the other hand, intracellular iron levels remain elevated during nerve regeneration and gradually decrease.
arxiv +1 more source
Model-based clustering for identifying disease-associated SNPs in case-control genome-wide association studies [PDF]
Genome-wide association studies (GWASs) aim to detect genetic risk factors for complex human diseases by identifying disease-associated single-nucleotide polymorphisms (SNPs). The traditional SNP-wise approach along with multiple testing adjustment is over-conservative and lack of power in many GWASs.
arxiv +1 more source
Diabetes compromises the bone marrow (BM) microenvironment and reduces the number of circulating CD34+ cells. Diabetic autonomic neuropathy (DAN) may impact the BM, because the sympathetic nervous system is prominently involved in BM stem cell ...
M. Albiero+11 more
semanticscholar +1 more source
Clinical features of autoimmune autonomic neuropathy with onset of acute autonomic nerve dysfunction
Background Autoimmune autonomic neuropathy with onset of acute autonomic nerve dysfunction is often misdiagnosed because its main symptoms are syncope and gastrointestinal motility disorder.
Fan LI+11 more
doaj
Severe neuropathy in a patient with ischemic heart disease and type 2 diabetes
The article describes a variety of severe clinical manifestations of diabetic autonomic neuropathy in patients with type 2 diabetes mellitus and coronary heart disease.
Victor Yur'evich Kalashnikov+4 more
doaj +1 more source