Results 81 to 90 of about 64,174 (311)

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

open access: yesInterdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui   +12 more
wiley   +1 more source

Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes

open access: yesMediators of Inflammation, 2020
Introduction. A neuroimmune communication exists, and compelling evidence suggests that diabetic neuropathy and systemic inflammation are linked. Our aims were (1) to investigate biomarkers of the ongoing inflammation processes including cytokines ...
Anne-Marie L. Wegeberg   +8 more
doaj   +1 more source

Clinical, manometric, genetic, and histologic associations in pediatric intestinal pseudo‐obstruction: A case series

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric intestinal pseudo‐obstruction (PIPO) is a severe bowel motility disorder characterized by impaired propulsion of gastrointestinal contents without mechanical obstruction. PIPO encompasses congenital and acquired disorders, including neuropathies, myopathies, and mesenchymopathies.
Sharon Wolfson   +8 more
wiley   +1 more source

THE EFFICACY OF MELDONIUM IN PATIENTS WITH CHRONIC HEART FAILURE OF ISCHEMIC ETIOLOGY WITH COMORBIDITIES

open access: yesМедицинский совет, 2017
Нeart failure is common both in cardiac and noncardiac disease. We conducted a study that showed high efficacy and safety of meldonium in patients with heart failure and comorbidity.
M. E. Statsenko   +4 more
doaj   +1 more source

Distinction and mutual Influences between Parkinson's Disease‐related and unrelated Chronic Pain

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Chronic pain (i.e. > 3 months) is a common nonmotor symptom in patients with Parkinson's disease (PD), but the attribution to PD is critical for further treatment. Objectives We explored the PD Pain Classification System (PD‐PCS) criteria for the diagnosis of PD‐related pain and mutual influences between PD‐related and PD‐unrelated ...
Jonathan Hunger   +11 more
wiley   +1 more source

Heart rate variability and target organ damage in hypertensive patients [PDF]

open access: yes, 2012
Background: We evaluated the association between linear standard Heart Rate Variability (HRV) measures and vascular, renal and cardiac target organ damage (TOD).
2003 European Society of Hypertension   +56 more
core   +4 more sources

Sympathetic Shift and Insular Alteration: Unravelling the Link Between Anxiety and Heart Rate Variability in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Anxiety and autonomic dysfunction are frequent non‐motor symptoms of Parkinson's disease (PD). Their relationship, as well as the neural mechanisms underlying this relationship, remain unexplored. Objectives We aimed to investigate the relationship between cardiovascular functions and anxiety in PD and the structural neural changes ...
Lucia Ricciardi   +9 more
wiley   +1 more source

Clinical features of autoimmune autonomic neuropathy with onset of acute autonomic nerve dysfunction

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2020
Background Autoimmune autonomic neuropathy with onset of acute autonomic nerve dysfunction is often misdiagnosed because its main symptoms are syncope and gastrointestinal motility disorder.
Fan LI   +11 more
doaj  

Severe neuropathy in a patient with ischemic heart disease and type 2 diabetes

open access: yesСахарный диабет, 2016
The article describes a variety of severe clinical manifestations of diabetic autonomic neuropathy in patients with type 2 diabetes mellitus and coronary heart disease.
Victor Yur'evich Kalashnikov   +4 more
doaj   +1 more source

Clinical, Genetic, and Imaging Characteristics of SCA27B: Insights from a Large Dutch Cohort

open access: yesMovement Disorders, EarlyView.
Abstract Background Deep intronic GAA repeat expansions in intron 1 of the FGF14 gene were identified in 2023 as cause of late‐onset cerebellar ataxia. Since then, GAA‐FGF14‐related ataxia (SCA27B) has emerged as one of the most common genetic causes of late‐onset cerebellar ataxia.
Teije H. van Prooije   +26 more
wiley   +1 more source

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