Results 81 to 90 of about 470,864 (273)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
IEEE AccessThis study investigates the potential of open-source Large Language Models (LLMs) to enhance the accessibility and understanding of complex legal information.
Patricio Santiago Garcia-Montero +3 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Study on Following Car Model with Different Driving Styles Based on Proximal PolicyOptimization Algorithm [PDF]
Jisuanji kexueAutonomous driving plays a crucial role in reducing traffic congestion and improving driving comfort.It remains of significant research importance to enhance public acceptance of autonomous driving technology.Customizing different driving styles for ...
YAN Xin, HUANG Zhiqiu, SHI Fan, XU Heng
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Developing a Risk Recognition System Based on a Large Language Model for Autonomous Driving
Engineering ProceedingsAutonomous driving systems have the potential to reduce traffic accidents dramatically; however, conventional modules often struggle to accurately detect risks in complex environments.
Donggyu Min, Dong-Kyu Kim
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Effects of Anthropomorphic Driving Vehicles on Traffic Flow
Applied SciencesAutonomous driving has many positive impacts, such as improving driver and passenger safety, comfort, and traffic efficiency, but all these advantages are based on people’s trust and acceptance of this mode of driving. Anthropomorphic driving can enhance
Xiaoyi Ma +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshuThis paper aims to clarify the behavior and damage conditions of batteries when multi-rotor unmanned aerial vehicles (drones) in horizontal flight collide with a structure to obtain the engineering knowledge that serves to consider the method of the ...
Kengo TAKAHASHI +3 more
doaj +1 more source