Results 81 to 90 of about 767,690 (291)

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

open access: yesAdvanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin   +18 more
wiley   +1 more source

Autonomous unmanned ships

open access: yes, 2022
Autonomni brodovi, odnosno “pametni brodovi”, jesu brodovi budućnosti. Osmišljeni su kako bi mogli ploviti bez posade, što bi donijelo mnoge prednosti, poput smanjena ljudskih havarija, smanjena troškova i ostale prednosti. Na autonomnim brodovima radili
Ahmetović, Melisa
core   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

open access: yesAdvanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao   +10 more
wiley   +1 more source

Cyber-Attacks Against the Autonomous Ship [PDF]

open access: yes, 2019
Autonomous ships transferring valuable cargoes and humans in a more efficient and cost effective manner will soon be state of the art technology. Yet, their ICT system architecture and operations have not been defined in full detail. Moreover, multiple cyber security issues remain open and should be addressed.
Georgios Kavallieratos   +2 more
openaire   +3 more sources

Interaction Between Manned and Autonomous Ships: Automation Transparency

open access: yes, 2019
Maritime Autonomous Surface Ships (MASS) is on the research agenda of several countries. In Norway a 120 TEU autonomous container feeder is currently being built. Hopes are attached to safety as well as costs and efficiency benefits.
Porathe, Thomas
core  

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

open access: yesAdvanced Science, EarlyView.
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran   +10 more
wiley   +1 more source

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

open access: yesAdvanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang   +8 more
wiley   +1 more source

Overview and analysis of regulatory framework for the application of autonomous vessels [PDF]

open access: yesTehnika
The notion of an autonomous ship has led to a reconsideration of the existing concept of the ship in terms of safety, security, design, crew, equipment, regulatory and participants in the transport process and in the entire supply chain.
Abođi Anita G.   +3 more
doaj   +1 more source

A Scalable Droplet Microfluidic Platform That Overcomes Large‐Cell Constraints for Long‐Term Plant Cell Culture and Embryogenesis Analysis

open access: yesAdvanced Science, EarlyView.
This work presents a large‐cell‐compatible droplet microfluidic platform that overcomes long‐standing barriers in plant cell culture by enabling high‐fidelity encapsulation, novel multilayer 3D droplet incubation for scalable long‐term culture, and support for the full developmental progression of large plant cells.
Arman Mirmiran   +10 more
wiley   +1 more source

Civil liability of the owner of autonomous ships due to ship collision [PDF]

open access: yesپژوهش های حقوق تطبیقی
Artificial intelligence is expanding rapidly in various sectors of the industry, including maritime transportation. However, the use of autonomous ships can reduce collisions, which are significantly caused by human errors.
asma jorfi   +2 more
doaj  

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