Results 201 to 210 of about 35,722 (281)

Glial cytokine modulation improves sleep and circadian disruption in female SAA knock‐in mice of Alzheimer's‐related pathology

open access: yesAlzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Sleep and circadian disturbances are early Alzheimer's disease (AD) features, yet mechanisms linking amyloid pathology, neuroinflammation, and sex differences remain unclear. METHODS We longitudinally assessed sleep, circadian rhythms, and cognition in female and male hAPPSAA knock‐in and control mice from 2 to 19 months using ...
Teresa Macheda   +18 more
wiley   +1 more source

Inhaled 5‐HT1B/1D Receptor Antagonist Attenuates Sumatriptan‐Induced Sensitization of Capsaicin‐Sensitive Lung Vagal Afferents: Implications for Preventing Sumatriptan‐Associated Adverse Chest Symptoms

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Our previous study suggests that sumatriptan‐induced chest discomfort is associated with hypersensitivity of CSLV afferents via 5‐HT1B/1D receptors on nerve endings. The present study demonstrates that inhaled 5‐HT1B/1D receptor antagonism suppresses this hypersensitivity without compromising antimigraine efficacy, supporting local pulmonary antagonism
Nai‐Ju Chan   +3 more
wiley   +1 more source

Assessing Recreational Safety of Urban Marine Waters: Long‐Term Coliform and Enterococcus Analysis

open access: yesWater Environment Research, Volume 98, Issue 4, April 2026.
Mapped data (site means) representing three major indicator bacteria in Jamaica Bay, New York, from 1965 to 2019 which can impact human and environmental health, highlighting elevated TCC and FCC in the northern estuary compared with EC. Enterococcus values (EC, green circles ) total coliform count (TCC, blue squares ) and fecal coliform count (FCC ...
Mark J. Ringenary   +2 more
wiley   +1 more source

Surgery in space: The ultimate frontier

open access: yes
Experimental Physiology, EarlyView.
Mohamad Bashir   +5 more
wiley   +1 more source

As above, so below: A perspective into the application of land‐forest monitoring methods for the assessment of marine animal forests

open access: yesMethods in Ecology and Evolution, Volume 17, Issue 4, Page 1124-1142, April 2026.
Abstract Marine animal forests (MAFs) are benthic ecosystems dominated by vertically structuring filter‐ and suspension‐feeders. As terrestrial forests, they are considered biodiversity hotspots, forming canopies, serving as a refuge, nursery, reproduction and feeding shelters for many species.
Torcuato Pulido Mantas   +9 more
wiley   +1 more source

Astrocyte Proximity Protects Synapses From Human Amyloid‐Beta Induced Degeneration in a Mouse Ex Vivo Model of Early Alzheimer's Disease

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 7, April 2026.
Alzheimer's disease (AD) is the most common cause of dementia, affecting over 35 million people worldwide. A key feature of AD is the loss of synapses—the connections between brain cells—which strongly correlates with cognitive decline. We sought to investigate the role of astrocytes in mouse organotypic cultures challenged with brain homogenate (BH ...
Francesco Gobbo   +11 more
wiley   +1 more source

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