Results 271 to 280 of about 57,206 (302)

Heat-shock chaperone HSPB1 mitigates poly-glycine-induced neurodegeneration via restoration of autophagic flux. [PDF]

Autophagy
Ding N, Song Y, Zhang Y, Yu W, Li X, Li W, Li L.   +6 more
europepmc   +1 more source

ROS-DRP1-mediated excessive mitochondrial fission and autophagic flux inhibition contribute to heat stress-induced apoptosis in goat Sertoli cells. [PDF]

J Anim Sci Biotechnol
Wen F, Gao J, Zhang G, Guo S, Zhang X, Han S, Feng X, Chen X, Hu J.   +8 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Assessing autophagic flux in yeast

2021
Abstract Autophagy is an intracellular recycling program that is ubiquitously present in eukaryotes, where it is crucial for the maintenance of cellular homeostasis. Thereby, superfluous or damaged proteins, organelles and cytoplasmic portions are targeted either in bulk or selectively for delivery to the lysosome (or vacuole in yeast).
Katharina, Kainz, Tobias, Pendl, Frank, Madeo, Didac, Carmona-Gutierrez   +3 more
openaire   +2 more sources

Autophagic flux assessment by immunoblot

2021
Autophagy is one of the main adaptive mechanisms to maintain cellular homeostasis in response to multiple stresses. During autophagy diverse cellular components such as damaged organelles or superfluous proteins are targeted for lysosomal degradation.
Qi, Wu, Ai-Ling, Tian, Hui, Pan, Oliver, Kepp, Guido, Kroemer   +4 more
openaire   +2 more sources

Autophagic flux in glioblastoma cells

International Journal of Radiation Biology, 2016
To establish metabolic context for radiation sensitivity by measuring autophagic flux in two different glioblastoma (GBM) cell lines. Clonogenic survival curve analysis of U87 or U251 cells exposed to γ radiation, fast neutrons, a mixed energy neutron beam (METNB) or Auger electrons from a gadolinium neutron capture (GdNC) reaction suggested other ...
Linda S, Yasui, Maria, Duran, Christine, Andorf, Thomas, Kroc, Kathryn, Owens, Kelsie, Allen-Durdan, Andrew, Schuck, Scott, Grayburn, Richard, Becker   +8 more
openaire   +2 more sources

Autophagic Flux Detection: Significance and Methods Involved

2021
Macroautophagy is an important biological process in eukaryotic cells by which longevity proteins, misfolded proteins, and damaged organelles are degraded. The autophagy process consists of three key steps: (1) the formation of autophagosomes; (2) the fusion of the autophagosomes with lysosomes; and (3) the degradation of the contents of autolysosomes.
Xiao-Wei, Zhang, Xiao-Xi, Lv, Ji-Chao, Zhou, Cai-Cai, Jin, Lu-Yao, Qiao, Zhuo-Wei, Hu   +5 more
openaire   +2 more sources

Analyzing Autophagic Flux in Nerve Cultures

2018
Autophagy is a key cellular mechanism involved in the degradation of long-lived proteins and organelles. We and others have previously shown that Schwann cells are able to degrade their own myelin by a form of selective autophagy, or myelinophagy.
Miguel, Tamayo Caro, Marta, Palomo Irigoyen, Encarnación, Pérez Andrés, Adrián, Barreira Manrique, Marta, Varela Rey, Ashwin, Woodhoo   +5 more
openaire   +2 more sources

TLR9 sustains autophagic flux

Science Signaling, 2016
TLR9 recognizing mitochondrial DNA sustains autophagic flux by functioning as a signaling adaptor protein at lysosomes.
openaire   +1 more source

Autophagic Flux Assessment in Colorectal Cancer Cells

2018
Autophagy protects colorectal cancer cells against therapeutic intervention. Autophagy is a continuous process, and autophagic flux requires both autophagosome synthesis and their subsequent degradation at lysosomes. Hence, cells with elevated autophagic flux display both rapid autophagosome generation and degradation.
Annie, Lauzier, Steve, Jean
openaire   +2 more sources

Autophagy and Autophagic Flux in Tumor Cells

2014
Macroautophagy (hereafter referred to as autophagy), a central mechanism mediating the lysosomal degradation of cytoplasmic components, can be stimulated by a wide panel of adverse stimuli, including a panoply of anticancer agents. The central autophagic organelle is the autophagosome, a double membrane-bound vacuole that sequesters the cytoplasmic ...
Nicolas, Dupont, Idil, Orhon, Chantal, Bauvy, Patrice, Codogno   +3 more
openaire   +2 more sources