The 1:2 complex between RavZ and LC3 reveals a mechanism for deconjugation of LC3 on the phagophore membrane [PDF]
Autophagy, 2017 Hosts utilize macroautophagy/autophagy to clear invading bacteria; however, bacteria have also developed a specific mechanism to survive by manipulating the host cell autophagy mechanism.
Do Hoon Kwon, Sulhee Kim, Yang Ouk Jung
exaly +4 more sources
Properties, compatibility, environmental benefits and future directions of limestone calcined clay cement (LC3) concrete: A review [PDF]
Journal of Building Engineering, 2023 This review paper provides a comprehensive analysis of the production, properties and applications of Limestone Calcined Clay Cement (LC3). The paper begins with an introduction to LC3 and its importance in reducing carbon emissions in the cement ...
Salim Barbhuiya +2 more
exaly +2 more sources
E1-like activating enzyme Atg7 is preferentially sequestered into p62 aggregates via its interaction with LC3-I. [PDF]
PLoS ONE, 2013 p62 is constitutively degraded by autophagy via its interaction with LC3. However, the interaction of p62 with LC3 species in the context of the LC3 lipidation process is not specified.
Wentao Gao +3 more
doaj +3 more sources
The carboxyl-terminal amino acids render pro-human LC3B migration similar to lipidated LC3B in SDS-PAGE. [PDF]
PLoS ONE, 2013 LC3 is widely used marker for macroautophagy assays. After translation pro-LC3 is processed by Atg4 to expose C-terminal glycine residue for downstream conjugation reactions to accomplish the conversion of LC3-I to LC3-II. SDS-PAGE based Western blot (Wb)
Wei Wang +4 more
doaj +3 more sources
Macrophages target Salmonella by Lc3-associated phagocytosis in a systemic infection model [PDF]
Autophagy, 2019 Innate immune defense against intracellular pathogens, like Salmonella, relies heavily on the autophagy machinery of the host. This response is studied intensively in epithelial cells, the target of Salmonella during gastrointestinal infections. However,
Samrah Masud +2 more
exaly +2 more sources
LC3-associated phagocytosis [PDF]
Autophagy, 2014 A recent report from our group has described that upon engulfment of pathogens, a subset of phagosomes is formed to preserve antigens for prolonged presentation on MHC class II molecules.
Romao, Susana, Münz, Christian
core +5 more sources
Nucleocytoplasmic distribution and dynamics of the autophagosome marker EGFP-LC3. [PDF]
PLoS ONE, 2010 The process of autophagy involves the formation of autophagosomes, double-membrane structures that encapsulate cytosol. Microtubule-associated protein light chain 3 (LC3) was the first protein shown to specifically label autophagosomal membranes in ...
Kimberly R Drake +2 more
doaj +2 more sources
Semisynthesis of autophagy protein LC3 conjugates
Bioorganic & Medicinal Chemistry, 2017 Autophagy is a conserved catabolic process involved in the elimination of proteins, organelles and pathogens. Autophagosome formation is the key process in autophagy. Lipidated Atg8/LC3 proteins that are conjugated to phosphatidylethanolamine (PE) play a
Aimin Yang +9 more
core +6 more sources
Energies, 2023 This work studies a fluidization system through cold experiments by using a mixture of rice husk and sand to investigate three parameters: type of bed distributor (perforated plate and plate with Tuyere-type injectors), sand granulometry (mean diameters ...
Fernando M. P. Balestieri +2 more
doaj +1 more source
Energies, 2023 Global warming might be mitigated if emissions were interrupted through carbon capture technologies, as there is a significant amount of comprehensive studies on them.
Rubens C. Toledo +3 more
doaj +1 more source