Results 1 to 10 of about 98,607 (352)
How to Interpret LC3 Immunoblotting
Autophagy, 2007 Microtubule-associated protein light chain 3 (LC3) is now widely used to monitor autophagy. One approach is to detect LC3 conversion (LC3-I to LC3-II) by immunoblot analysis because the amount of LC3-II is clearly correlated with the number of ...
N. Mizushima, T. Yoshimori
semanticscholar +3 more sources
Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein
Angewandte Chemie - International Edition, 2021 The autophagic ubiquitin-like protein LC3 functions through interactions with LC3-interaction regions (LIRs) of other autophagy proteins including autophagy receptors, which stands out as a promising protein-protein interaction (PPI) target for the ...
Yongjun Dang +2 more
exaly +2 more sources
Beyond autophagy: LC3-associated phagocytosis and endocytosis
Science Advances, 2022 Noncanonical functions of the autophagy machinery in pathways including LC3-associated phagocytosis and LC3-associated endocytosis have garnered increasing interest in both normal physiology and pathobiology.
C. Peña-Martínez +2 more
semanticscholar +3 more sources
LC3-Associated Phagocytosis and Inflammation [PDF]
Journal of Molecular Biology, 2017 LC3-associated phagocytosis (LAP) is a novel form of non-canonical autophagy where LC3 (microtubule-associated protein 1A/1B-light chain 3) is conjugated to phagosome membranes using a portion of the canonical autophagy machinery. The impact of LAP to immune regulation is best characterized in professional phagocytes, in particular macrophages, where ...
Larissa Dias Da Cunha +2 more
exaly +3 more sources
LC3-associated phagocytosis at a glance
Journal of Cell Science, 2019 Classically, canonical autophagy has been considered a survival mechanism initiated in response to nutrient insufficiency. We now understand that autophagy functions in multiple scenarios where it is necessary to maintain homeostasis. Recent evidence has
Bradlee L. Heckmann, D. Green
semanticscholar +4 more sources
LC3-associated endocytosis and the functions of Rubicon and ATG16L1
Science Advances, 2022 LC3-associated endocytosis (LANDO) is a noncanonical function of the autophagy machinery, in which LC3 (microtubule-associated protein light chain) is conjugated to rab5-positive endosomes, using a portion of the canonical autophagy pathway.
J. Magné, D. Green
semanticscholar +3 more sources
Identifying an essential role of nuclear LC3 for autophagy [PDF]
Autophagy, 2015 MAP1LC3/LC3 (microtubule-associated protein 1 light chain 3), a mammalian ortholog of yeast Atg8, is a key protein contributing to major steps of autophagy. It has been recognized for a long time that LC3 is abundant in the nucleus despite the fact that it functions primarily in the cytoplasm where the autophagosomes and autolysosomes arise.
Rui Huang, Wei Liu
exaly +3 more sources
Energies, 2023 This work studies a fluidization system through cold experiments by using a mixture of rice husk and sand to investigate three parameters: type of bed distributor (perforated plate and plate with Tuyere-type injectors), sand granulometry (mean diameters ...
Fernando M. P. Balestieri +2 more
doaj +1 more source
Energies, 2023 Global warming might be mitigated if emissions were interrupted through carbon capture technologies, as there is a significant amount of comprehensive studies on them.
Rubens C. Toledo +3 more
doaj +1 more source
South African Journal of Chemical Engineering, 2022 Solid carbonates can be formed by indirect mineral carbonation using the pH swing method for CO2 storage. It occurs at low temperatures and pressures in four stages: acid dissolution, purification, carbonation, and recovery.
Kely R.M. Vieira +6 more
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