Results 1 to 10 of about 80,599 (213)

Prognostic impact of autophagy biomarkers for cutaneous melanoma. [PDF]

Frontiers in Oncology, 2016
Prognosis and survival for malignant melanoma is highly dependent on early diagnosis and treatment. While the American Joint Committee on Cancer (AJCC) criteria provides a means of staging melanomas and guiding treatment approaches, it is unable to ...
Diana Yao Li Tang, Robert Ellis, Robert Ellis, Penny Lovat   +3 more
doaj   +2 more sources

Role of Autophagy Biomarkers In Burn-Age Estimation and Progression [PDF]

Academic Forensic Pathology, 2019
Heba A Yassa
exaly   +2 more sources

Non-invasive biomarkers for brain aging: the role of autophagy-related microRNAs in plasma exosomes

Frontiers in Molecular Neuroscience
AimThis study aimed to identify autophagy-related microRNAs (miRNAs) in plasma exosomes as non-invasive biomarkers for brain aging and explore their potential to improve early detection of age-associated neurodegeneration.
Zhiming Lu, Shuyi Yu
exaly   +3 more sources

Identification of the relationship between biomarkers of autophagy, apoptosis and inflammation in the acute period of atherothrombotic ischemic stroke

Медицинская иммунология, 2023
The postischemic inflammatory response plays a significant role in the pathogenesis of acute ischemic stroke (IS). It has been established that acute IS is accompanied by aseptic inflammation, which induces the activation of costimulatory molecules in ...
A. V. Lugovaya, N. M. Kalinina, A. M. Ivanov, Yu. V. Nikitin, I. А. Sukhina, V. F. Mitreikin, E. V. Semenova   +6 more
doaj   +1 more source

Assessment of the dynamics of autophagy and apoptosis biomarkers in the acute period of ischemic stroke using flow cytometry

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2022
The objective was to conduct a comparative analysis of the dynamics of biomarkers of apoptosis and autophagy in the eripheral blood of patients in the acute period of ischemic stroke (IS) and compare it with the dynamics of the severity of neurological ...
A. V. Lugovaya, Yu. V. Emanuel, A. V. Artemova, E. V. Semenova, V. V. Semenova   +4 more
doaj   +1 more source

Machine learning and bioinformatics analysis to identify autophagy-related biomarkers in peripheral blood for rheumatoid arthritis

Frontiers in Genetics, 2023
Background: Although rheumatoid arthritis (RA) is a common autoimmune disease, the precise pathogenesis of the disease remains unclear. Recent research has unraveled the role of autophagy in the development of RA.
Guoqi Dong, Hui Gao, Yingqi Chen, Huayuan Yang   +3 more
doaj   +1 more source

Unravelling the roles of Autophagy in OSCC: A renewed perspective from mechanisms to potential applications

Frontiers in Pharmacology, 2022
Oral squamous cell carcinoma (OSCC) is associated with a low survival rate and a high disability rate, making it a serious health burden, particularly in Southeast Asian countries.
Qiutong Gou, Ling-Li Zheng, Haixia Huang
doaj   +1 more source

Salinomycin Triggers Human Colorectal Cancer HCT116 Cell Death by Targeting Unfolded Protein Responses and Autophagy Pathways [PDF]

Iranian Journal of Colorectal Research, 2023
Background: Autophagy and the unfolded protein response (UPR) are important pathways in colorectal tumorigenesis and drug resistance, rendering them as potential therapeutic targets for treating this cancer.
Mozhdeh Zamani, Morvarid Siri, Sanaz Dastghaib, Pooneh Mokarram   +3 more
doaj   +1 more source

Clustering analysis revealed the autophagy classification and potential autophagy regulators' sensitivity of pancreatic cancer based on multi‐omics data

Cancer Medicine, 2023
Background Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy and is unresponsive to conventional therapeutic modalities due to its high heterogeneity, expounding the necessity, and priority of searching for effective biomarkers and drugs ...
Yonghao Chen, Jialin Meng, Xiaofan Lu, Xiao Li, Chunhui Wang   +4 more
doaj   +1 more source

Identification and verification of three autophagy-related genes as potential biomarkers for the diagnosis of psoriasis

Scientific Reports, 2023
Psoriasis vulgaris is the most common form of the four clinical types. However, early diagnosis of psoriasis vulgaris is difficult due to the lack of effective biomarkers.
Ailing Zou, Yongjun Chen, Tangsheng Liu, Ting Yang, Bei Zhou   +4 more
doaj   +1 more source