Results 1 to 10 of about 75,479 (157)
Prognostic Impact of Autophagy Biomarkers for Cutaneous Melanoma [PDF]
Frontiers in Oncology, 2016 Prognosis and survival for malignant melanoma is highly dependent on early diagnosis and treatment. While the American Joint Committee on Cancer (AJCC) criteria provides a means of staging melanomas and guiding treatment approaches, it is unable to ...
R Ellis, Penny E Lovat, Lovat Penny E
exaly +8 more sources
Role of Autophagy Biomarkers In Burn-Age Estimation and Progression [PDF]
Academic Forensic Pathology, 2019 Background: Determination of time passed since burn injury in the living is critical in forensic science. Autophagy biomarkers and vitronectin can play an important role in determination of the age of burn injuries through their levels in the tissue ...
Heba A Yassa
exaly +5 more sources
Tumors Responsive to Autophagy-Inhibition: Identification and Biomarkers [PDF]
Cancers, 2020 Recent advances in cancer treatment modalities reveal the limitations of the prevalent “one-size-fits-all” therapies and emphasize the necessity to develop personalized approaches. In this perspective, identification of predictive biomarkers and intrinsic vulnerabilities are an important advancement for further therapeutic strategies.
Lydie M O Barbeau +2 more
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Biomarkers of Chondrocyte Apoptosis and Autophagy in Osteoarthritis [PDF]
International Journal of Molecular Sciences, 2015 Cell death with morphological and molecular features of apoptosis has been detected in osteoarthritic (OA) cartilage, which suggests a key role for chondrocyte death/survival in the pathogenesis of OA. Identification of biomarkers of chondrocyte apoptosis may facilitate the development of novel therapies that may eliminate the cause or, at least, slow ...
Giuseppe Musumeci +2 more
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Autophagy-related IFNG is a prognostic and immunochemotherapeutic biomarker of COAD patients
Frontiers in Immunology, 2023 BackgroundNumerous studies have shown autophagy affects cellular immune responses. This study aims to explore prognosis and immunotherapeutic biomarkers related to autophagy in colon adenocarcinoma (COAD).MethodsBased on R software, we performed the ...
Taohua Yue +6 more
doaj +3 more sources
Clinical Applications of Autophagy Proteins in Cancer: From Potential Targets to Biomarkers [PDF]
International Journal of Molecular Sciences, 2017 Autophagy, a lysosome-mediated intracellular degradation and recycling pathway, plays multiple context-dependent roles in tumorigenesis and treatment resistance. Encouraging results from various preclinical studies have led to the initiation of numerous clinical trials with the intention of targeting autophagy in various cancers. Accumulating knowledge
Svetlana Bortnik +2 more
exaly +3 more sources
Identification of autophagy-related key biomarkers in caerulein induced acute pancreatitis: In silico and in vivo study. [PDF]
PLoS ONEBackgroundDysregulated autophagy is known to play a crucial role in the pathogenesis of Acute pancreatitis (AP). However, its specific mechanisms remain unclear.
Xinzhuang Shen +6 more
doaj +2 more sources
BiomedicinesAutophagy is a form of programmed cell degradation that enables the maintenance of homeostasis in response to extracellular stress stimuli. Autophagy is primarily activated by starvation and mediates the degradation, removal, or recycling of cell ...
Ling Zhu +2 more
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Autophagy-related genes are potential diagnostic biomarkers for dermatomyositis [PDF]
Annals of Translational Medicine, 2022 Dermatomyositis (DM) is an autoimmune disease mainly diagnosed by its symptoms and a physical examination, with only some subtypes of DM showing clear molecular changes. To date, few biomarkers have been identified to assess DM progression. Autophagy-related genes have been significantly correlated with inflammation, several types of autoimmune ...
Wang, Le, Fang, Dalang, Liu, Yuan
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Atg16L1 as a Novel Biomarker and Autophagy Gene for Diabetic Retinopathy [PDF]
Journal of Diabetes Research, 2021 Objective. Accumulating evidence suggests the critical role of autophagy in the pathogenesis of diabetic retinopathy (DR). In the current study, we aim to identify autophagy genes involved in DR via microarray analyses. Methods. Gene microarrays were performed to identify differentially expressed lncRNAs/mRNAs between normal and DR retinas.
Xinxiao Gao +5 more
openaire +3 more sources