Results 11 to 20 of about 80,599 (213)

Autophagy-related IFNG is a prognostic and immunochemotherapeutic biomarker of COAD patients

Frontiers in Immunology, 2023
BackgroundNumerous studies have shown autophagy affects cellular immune responses. This study aims to explore prognosis and immunotherapeutic biomarkers related to autophagy in colon adenocarcinoma (COAD).MethodsBased on R software, we performed the ...
Taohua Yue, Yunlong Cai, Jing Zhu, Yucun Liu, Shanwen Chen, Pengyuan Wang, Long Rong   +6 more
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Journey to the Center of the Fetal Brain: Environmental Exposures and Autophagy

Frontiers in Cellular Neuroscience, 2018
Fetal brain development is known to be affected by adverse environmental exposures during pregnancy, including infection, inflammation, hypoxia, alcohol, starvation, and toxins.
Jun Lei, Pilar Calvo, Richard Vigh, Irina Burd   +3 more
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New insights into autophagy in inflammatory subtypes of asthma

Frontiers in Immunology, 2023
Asthma is a heterogeneous airway disease characterized by airway inflammation and hyperresponsiveness. Autophagy is a self-degrading process that helps maintain cellular homeostasis.
Hongna Dong, Wei Yang, Wei Li, Simin Zhu, Ling Zhu, Peng Gao, Yuqiu Hao   +6 more
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Development of a Machine Learning-Based Autophagy-Related lncRNA Signature to Improve Prognosis Prediction in Osteosarcoma Patients

Frontiers in Molecular Biosciences, 2021
BackgroundOsteosarcoma is a frequent bone malignancy in children and young adults. Despite the availability of some prognostic biomarkers, most of them fail to accurately predict prognosis in osteosarcoma patients.
Guang-Zhi Zhang, Guang-Zhi Zhang, Guang-Zhi Zhang, Zuo-Long Wu, Zuo-Long Wu, Chun-Ying Li, En-Hui Ren, En-Hui Ren, En-Hui Ren, Wen-Hua Yuan, Wen-Hua Yuan, Ya-Jun Deng, Ya-Jun Deng, Qi-Qi Xie, Qi-Qi Xie, Qi-Qi Xie   +15 more
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Baseline extracellular vesicle miRNA-30c and autophagic CTCs predict chemoradiotherapy resistance and outcomes in patients with lung cancer

Biomarker Research, 2023
Concurrent chemoradiotherapy (cCRT) is the mainstay of treatment for patients diagnosed with locally advanced non-small cell lung cancer (NSCLC). One significant challenge in the effectiveness of this therapy is the potential development of resistance ...
Diego de Miguel-Perez, Francisco Gabriel Ortega, Rosario Guerrero Tejada, Antonio Martínez-Única, Christine B. Peterson, Alessandro Russo, Muthukumar Gunasekaran, Andres F. Cardona, Victor Amezcua, Jose Antonio Lorente, Jose Expósito Hernández, Christian Rolfo, Maria Jose Serrano   +12 more
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The regulatory roles of circular RNAs via autophagy in ischemic stroke

Frontiers in Neurology, 2022
Ischemic stroke (IS) is a severe disease with a high disability, recurrence, and mortality rates. Autophagy, a highly conserved process that degrades damaged or aging organelles and excess cellular components to maintain homeostasis, is activated during ...
Xiaoqin Li, Lingfei Li, Xiaoli Si, Zheng Zhang, Zhumei Ni, Yongji Zhou, Keqin Liu, Wenqing Xia, Yuyao Zhang, Xin Gu, Jinyu Huang, Congguo Yin, Congguo Yin, Anwen Shao, Anwen Shao, Lin Jiang, Lin Jiang   +16 more
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Identification of a Novel Defined Immune-Autophagy-Related Gene Signature Associated With Clinical and Prognostic Features of Kidney Renal Clear Cell Carcinoma

Frontiers in Molecular Biosciences, 2021
Background: As a common cancer of the urinary system in adults, renal clear cell carcinoma is metastatic in 30% of patients, and 1–2 years after diagnosis, 60% of patients die.
Guangyuan Zhang, Guangyuan Zhang, Lei Zhang, Lei Zhang, Si Sun, Ming Chen, Ming Chen, Ming Chen   +7 more
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Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot

Biology, 2020
Autophagy is a highly conserved degradation mechanism that is essential for maintaining cellular homeostasis. In human disease, autophagy pathways are frequently deregulated and there is immense interest in targeting autophagy for therapeutic approaches.
Magali Humbert, María Morán, Patricia de la Cruz-Ojeda, Jordi Muntané, Tabea Wiedmer, Nadezda Apostolova, Sharon L. McKenna, Guillermo Velasco, Walter Balduini, Leopold Eckhart, Bassam Janji, Belém Sampaio-Marques, Paula Ludovico, Eva Žerovnik, Rupert Langer, Aurel Perren, Nikolai Engedal, Mario P. Tschan   +17 more
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Non-coding RNAs: The recently accentuated molecules in the regulation of cell autophagy for ovarian cancer pathogenesis and therapeutic response

Frontiers in Pharmacology, 2023
Autophagy is a self-recycling and conserved process, in which the senescent cytoplasmic components are degraded in cells and then recycled to maintain homeostatic balance.
Bi Peng, Jing Li, Yuanliang Yan, Yuanhong Liu, Qiuju Liang, Qiuju Liang, Wei Liu, Wei Liu, Abhimanyu Thakur, Kui Zhang, Zhijie Xu, Jian Wang, Fan Zhang   +12 more
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The dynamics of biomarkers of autophagy and neuroinflammation in the acute period of atherothrombotic ischemic stroke

Медицинская иммунология
Postischemic neuroinflammation is a critical pathophysiological process within the entire pattern of cerebral ischemia. It is characterized by microglial and astroglial activation and is accompanied by disturbances in the innate and adaptive immune ...
A. V. Lugovaya, N. M. Kalinina, A. M. Ivanov, Yu. V. Nikitin, I. A. Sukhina, V. P. Mitreikin, S. Sh. Zabirov, G. E. Kirilkin   +7 more
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