Results 11 to 20 of about 63,338 (120)
Evaluating Autophagy in Preimplantation Embryos
Autophagy is an essential cellular degradation pathway in the mammalian preimplantation embryo. In this review, the process of autophagy is outlined and its function pertaining to preimplantation embryos is discussed.
Zuleika C. L. Leung +4 more
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Regulation of autophagy-related gene expressions by Trans-chalcone in the lungs of adult male rats [PDF]
Background. Autophagy is responsible for maintaining cellular homeostasis by degrading and recycling macromolecules and unwanted intracellular components, such as damaged organelles.
Fatemeh Salehi Mazdeh +4 more
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Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [PDF]
Objective(s): Diabetes is a chronic disorder that occurs as a result of impaired glucose metabolism. In hyperglycaemic states, the balance between oxidative stress and antioxidant enzymes is disrupted leading to oxidative damage and cell death.
Farhad Eisvand +3 more
doaj +1 more source
p62/SQSTM1 droplets initiate autophagosome biogenesis and oxidative stress control
Selective autophagy contributes to the degradation of condensates, such as sequestosome 1-bodies, also called p62/SQSTM1-bodies. We showed that endogenous p62 forms gel-like structures, which serve as platforms for autophagosome formation and nuclear ...
Eeva-Liisa Eskelinen +2 more
doaj +1 more source
Many studies have focused on how autophagy plays an important role in intestinal homeostasis under pathological conditions. However, its role in the intestine during hibernation remains unclear.
Waseem Ali Vistro +9 more
doaj +1 more source
Aim: Acquired docetaxel (DOC) resistance of prostate cancer (PCa) is still a clinical problem. In addition to failure in chemotherapy treatment, it causes tumor recurrence.
Süleyman İlhan, Ferdi Oguz
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Size Effect in Lime-stone Calcined Clay Cement (LC3) incorporated Paver blocks: Mechanical and Durability Investigation [PDF]
Limestone calcined clay cement (LC3) is a novel and environmentally friendly cement that is a blend of OPC clinker, calcined clay, limestone, and gypsum.
Yadav Amit +4 more
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Venetoclax inhibits autophagy in chronic lymphocytic leukemia cells
Venetoclax (VCX) is a BCL2 inhibitor approved for treating B cell-derived leukemia, including chronic lymphocytic leukemia (CLL). VCX’s role in apoptosis induction is well-defined, whereas its other mechanistic roles need to be clarified. Autophagy is an
Yongqiang Chen +6 more
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Atg8ylation as a general membrane stress and remodeling response
The yeast Atg8 protein and its paralogs in mammals, mammalian Atg8s (mAtg8s), have been primarily appreciated for their participation in autophagy. However, lipidated mAtg8s, including the most frequently used autophagosomal membrane marker LC3B, are ...
Suresh Kumar, Jingyue Jia1, Vojo Deretic
doaj +1 more source
The objective was to conduct a comparative analysis of the dynamics of biomarkers of apoptosis and autophagy in the eripheral blood of patients in the acute period of ischemic stroke (IS) and compare it with the dynamics of the severity of neurological ...
A. V. Lugovaya +4 more
doaj +1 more source

