Results 11 to 20 of about 63,338 (120)

Evaluating Autophagy in Preimplantation Embryos

open access: yesAutophagy Reports, 2022
Autophagy is an essential cellular degradation pathway in the mammalian preimplantation embryo. In this review, the process of autophagy is outlined and its function pertaining to preimplantation embryos is discussed.
Zuleika C. L. Leung   +4 more
doaj   +1 more source

Regulation of autophagy-related gene expressions by Trans-chalcone in the lungs of adult male rats [PDF]

open access: yesمجله پزشکی دانشگاه علوم پزشکی تبریز
Background. Autophagy is responsible for maintaining cellular homeostasis by degrading and recycling macromolecules and unwanted intracellular components, such as damaged organelles.
Fatemeh Salehi Mazdeh   +4 more
doaj   +1 more source

Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [PDF]

open access: yesIranian Journal of Basic Medical Sciences
Objective(s): Diabetes is a chronic disorder that occurs as a result of impaired glucose metabolism. In hyperglycaemic states, the balance between oxidative stress and antioxidant enzymes is disrupted leading to oxidative damage and cell death.
Farhad Eisvand   +3 more
doaj   +1 more source

p62/SQSTM1 droplets initiate autophagosome biogenesis and oxidative stress control

open access: yesMolecular & Cellular Oncology, 2021
Selective autophagy contributes to the degradation of condensates, such as sequestosome 1-bodies, also called p62/SQSTM1-bodies. We showed that endogenous p62 forms gel-like structures, which serve as platforms for autophagosome formation and nuclear ...
Eeva-Liisa Eskelinen   +2 more
doaj   +1 more source

In Vivo Autophagy Up-Regulation of Small Intestine Enterocytes in Chinese Soft-Shelled Turtles during Hibernation

open access: yesBiomolecules, 2019
Many studies have focused on how autophagy plays an important role in intestinal homeostasis under pathological conditions. However, its role in the intestine during hibernation remains unclear.
Waseem Ali Vistro   +9 more
doaj   +1 more source

Dosetaksel Dirençli Prostat Kanseri Hücrelerinde Timokinon Tarafından Otofajik Hücre Ölümünün İndüklenmesi

open access: yesDüzce Tıp Fakültesi Dergisi, 2021
Aim: Acquired docetaxel (DOC) resistance of prostate cancer (PCa) is still a clinical problem. In addition to failure in chemotherapy treatment, it causes tumor recurrence.
Süleyman İlhan, Ferdi Oguz
doaj   +1 more source

Size Effect in Lime-stone Calcined Clay Cement (LC3) incorporated Paver blocks: Mechanical and Durability Investigation [PDF]

open access: yesE3S Web of Conferences
Limestone calcined clay cement (LC3) is a novel and environmentally friendly cement that is a blend of OPC clinker, calcined clay, limestone, and gypsum.
Yadav Amit   +4 more
doaj   +1 more source

Venetoclax inhibits autophagy in chronic lymphocytic leukemia cells

open access: yesAutophagy Reports, 2023
Venetoclax (VCX) is a BCL2 inhibitor approved for treating B cell-derived leukemia, including chronic lymphocytic leukemia (CLL). VCX’s role in apoptosis induction is well-defined, whereas its other mechanistic roles need to be clarified. Autophagy is an
Yongqiang Chen   +6 more
doaj   +1 more source

Atg8ylation as a general membrane stress and remodeling response

open access: yesCell Stress, 2021
The yeast Atg8 protein and its paralogs in mammals, mammalian Atg8s (mAtg8s), have been primarily appreciated for their participation in autophagy. However, lipidated mAtg8s, including the most frequently used autophagosomal membrane marker LC3B, are ...
Suresh Kumar, Jingyue Jia1, Vojo Deretic
doaj   +1 more source

Assessment of the dynamics of autophagy and apoptosis biomarkers in the acute period of ischemic stroke using flow cytometry

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2022
The objective was to conduct a comparative analysis of the dynamics of biomarkers of apoptosis and autophagy in the eripheral blood of patients in the acute period of ischemic stroke (IS) and compare it with the dynamics of the severity of neurological ...
A. V. Lugovaya   +4 more
doaj   +1 more source

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