Results 21 to 30 of about 63,437 (218)
Brazil has set a goal to reduce greenhouse gas (GHG) emissions, which is a significant opportunity to leverage calcium looping (CaL) technology for energy generation in natural gas power plants.
Rubens Coutinho Toledo +4 more
doaj +1 more source
Yan Zhou,1,* Yishu Xue,1,* Aihua Bao,1,* Lei Han,1 Wuping Bao,1 Chao Xia,2 Xue Tian,1 Min Zhang1 1Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai ...
Zhou Y +7 more
doaj
Autophagy: A necessary process during the Trypanosoma cruzi life-cycle
Autophagy is a well-conserved process of self-digestion of intracellular components. T. cruzi is a protozoan parasite with a complex life-cycle that involves insect vectors and mammalian hosts. Like other eukaryotic organisms, T.
Betiana Nebaí Salassa +1 more
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Evaluation of the expression of LC3-II and BECLIN1 genes of autophagy pathway in patients with hematological malignancies [PDF]
Background: Autophagy is a pathway for the degradation of cytoplasmic components, which plays an essential role in various cellular and physiological processes, including cell renewal and survival, and immune responses.
Hossein Ayatollahi +6 more
doaj
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Crystal structure of 25,27-dibenzyloxy-26-benzoyloxy-28-hydroxycalix[ 4]arene, C49H40O5
C49H40O5, triclinic, P1̅ (no. 2), a = 10.8865(2) Å, b = 18.2743(3) Å, c = 18.3545(3) Å, α = 85.166(1)°, β = 86.233(1)°, γ = 84.268(1)°, V = 3614.3 Å3, Z = 4, Rgt(F) = 0.054, wRref(F2) = 0.148, T = 120 K.
Kuhn P., Matt D., Toupet L., Louati A.
doaj +1 more source
The blood proteome of imminent lung cancer diagnosis
Identification of risk biomarkers may enhance early detection of smoking-related lung cancer. We measured between 392 and 1,162 proteins in blood samples drawn at most three years before diagnosis in 731 smoking-matched case-control sets nested within ...
The Lung Cancer Cohort Consortium (LC3)
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We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source

