Results 201 to 210 of about 79,616 (304)

Methyltransferase-like 3 suppresses phenotypic switching of vascular smooth muscle cells by activating autophagosome formation. [PDF]

Cell Prolif, 2023
Fang ZM, Zhang SM, Luo H, Jiang DS, Huo B, Zhong X, Feng X, Cheng W, Chen Y, Feng G, Wu X, Zhao F, Yi X.   +12 more
europepmc   +1 more source

Post-translational modulation of O-linked β-N-acetylglucosamine (O-GlcNAcylation) regulates autophagic activity and autophagosomes formation in mouse cortical astrocytes

, 2019
Md. Ataur Rahman, Hongik Hwang, Yunjung Cho, Hyewhon Rhim   +3 more
openalex   +1 more source

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

Med Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang, Yuying Mo, Zhishan Ling, Yuting Zeng, Qi Zhang, Shuqi Zheng, Shuyang Wen, Yupeng Xiao, Siying Long, Tingting Yang, Qianru Li, Wenjie Shi, Guozhi Huang, Qing Zeng   +13 more
wiley   +1 more source

VPS13A Deficiency Leads to Impaired Lipid Distribution and Alteration of Mitochondrial Calcium Homeostasis in Fibroblasts of VPS13A Disease Patients

Movement Disorders, EarlyView.
Abstract Background Membrane contact sites are crucial for the exchange of ions or lipids and thus are critical for the function and maintenance of organelles. VPS13A is a membrane‐residing, bridge‐like protein connecting two membranes to enable bulk lipid transfer. Loss‐of‐function mutations in the VPS13A gene cause VPS13A disease.
Dajana Grossmann, Adrian Spranger, Emily Fischer, Johanna W. Schubarth, Jenny Leopold, Hannes Glaß, Sebastian Klicker, My Uyen Dang Thi, Anna Elisabeth Bartalis, Andreas Hermann, Kevin Peikert   +10 more
wiley   +1 more source

p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response [PDF]

, 2021
Shun Kageyama, Sigurður Guðmundsson, Yu‐shin Sou, Yoshinobu Ichimura, Naoki Tamura, Saiko Kazuno, Takashi Ueno, Yoshiki Miura, Daisuke Noshiro, Manabu Abe, Tsunehiro Mizushima, Nobuaki Miura, Shujiro Okuda, Hozumi Motohashi, Jin‐A Lee, Kenji Sakimura, Tomoyuki Ohe, Nobuo N. Noda, Satoshi Waguri, Eeva‐Liisa Eskelinen, Masaaki Komatsu   +20 more
openalex   +1 more source

Inhibition of GATE-16 attenuates ATRA-induced neutrophil differentiation of APL cells and interferes with autophagosome formation

, 2013
Daniel Brigger, Bruce E. Torbett, Joy Chen, Martin F. Fey, Mario P. Tschan   +4 more
openalex   +1 more source

Autophagy and formation of tubulovesicular autophagosomes provide a barrier against nonviral gene delivery [PDF]

, 2013
Rebecca L Roberts, Wafa’ T. Al-Jamal, Matthew Whelband, Paul Thomas, Matthew Jefferson, Jeroen Van den Bossche, Penny P. Powell, Kostas Kostarelos, Thomas Wileman   +8 more
openalex   +1 more source

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

Phytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte, Sílvia Santos Pedrosa, P. Raaj Khusial, Ana Raquel Madureira   +3 more
wiley   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

Intracellular accumulation of tau inhibits autophagosome formation by activating TIA1-amino acid-mTORC1 signaling. [PDF]

Mil Med Res, 2022
Li MZ, Liu EJ, Zhou QZ, Li SH, Liu SJ, Yu HT, Pan QH, Sun F, He T, Wang WJ, Ke D, Feng YQ, Li J, Wang JZ.   +13 more
europepmc   +1 more source