Results 101 to 110 of about 286,383 (199)

Import of a Cytosolic Protein into Lysosomes by Chaperone-mediated Autophagy Depends on Its Folding State

, 2000
Natalia Salvador, Carmen Aguado, Martin Horst, Erwin Knecht   +3 more
openalex   +1 more source

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene [PDF]

, 2003
X. Qu
openalex   +1 more source

Enhanced cytotoxicity of T-DM1 in HER2-low carcinomas via autophagy inhibition. [PDF]

PLoS One
Zhang J, Chang X, Bai Y, Ge X, Yin K, Xin Q.   +5 more
europepmc   +1 more source

Targeting Senescence with Apigenin Improves Chemotherapeutic Efficacy and Ameliorates Age‐Related Conditions in Mice

Advanced Science, EarlyView.
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang, Qixia Xu, Zhirui Jiang, Rong Sun, Qun Wang, Sanhong Liu, Xin Luan, Judith Campisi, James L. Kirkland, Weidong Zhang, Yu Sun   +10 more
wiley   +1 more source

Autophagy and the cvt Pathway Both Depend on AUT9

, 2000
Thomas Lang, Steffen Reiche, Michael Straub, Monika Bredschneider, Michael Thumm   +4 more
openalex   +2 more sources

Defective autophagy leads to cancer [PDF]

, 2003
Aimee L. Edinger, Craig B. Thompson
openalex   +1 more source

RNA-binding proteins and autophagy in lung cancer: mechanistic insights and therapeutic perspectives. [PDF]

Discov Oncol
Lei X, Zheng Y, Su W.
europepmc   +1 more source

Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low‐Temperature Photothermal Therapy via Targeting HSP90‐TXNDC9 Interactions

Advanced Science, EarlyView.
Icaritin demonstrates broad antitumor effects by inhibiting colorectal cancer (CRC) cell proliferation, migration, invasion, and causing cell cycle arrest. It induces apoptosis by repressing autophagic flux through disrupting HSP90‐TXNDC9 interactions.
Dan He, Siliang Chen, Xiaoyun Wang, Xiang Wen, Changyang Gong, Lei Liu, Gu He   +6 more
wiley   +1 more source

Class III phosphoinositide 3-kinase–Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes [PDF]

, 2003
Amina Tassa, Marie Paule ROUX, Didier Attaix, Daniel Béchet   +3 more
openalex   +1 more source

Gut microbiota modulate intestinal inflammation by endoplasmic reticulum stress-autophagy-cell death signaling axis. [PDF]

J Anim Sci Biotechnol
He F, Zheng Y, Elsabagh M, Fan K, Zha X, Zhang B, Wang M, Zhang H.   +7 more
europepmc   +1 more source