Results 111 to 120 of about 523,293 (245)

Quantitative assessment of cell fate decision between autophagy and apoptosis [PDF]

open access: yes, 2017
Autophagy and apoptosis are cellular processes that regulate cell survival and death, the former by eliminating dysfunctional components in the cell, the latter by programmed cell death.
Bahar, Ivet   +6 more
core   +3 more sources

Mitochondrial metabolism and targeted treatment strategies in ischemic-induced acute kidney injury

open access: yesCell Death Discovery
Ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI). The kidney is susceptible to IRI under several clinical conditions, including hypotension, sepsis, and surgical procedures, such as partial nephrectomy and kidney ...
Yongming Chen   +6 more
doaj   +1 more source

Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA. [PDF]

open access: yes, 2014
Macroautophagy (hereafter autophagy) is a key pathway in neurodegeneration. Despite protective actions, autophagy may contribute to neuron demise when dysregulated.
Batlevi, Yakup   +11 more
core  

Inhibition of Autophagy Signaling via 3-methyladenine Rescued Nicotine-Mediated Cardiac Pathological Effects and Heart Dysfunctions. [PDF]

open access: yes, 2020
Rationale: Cigarette smoking is a well-established risk factor for myocardial infarction and sudden cardiac death. The deleterious effects are mainly due to nicotine, but the mechanisms involved and theranostics remain unclear.
Fu, Yingjie   +7 more
core  

Lysosome-mediated processing of chromatin in senescence [PDF]

open access: yes, 2013
Cellular senescence is a stable proliferation arrest, a potent tumor suppressor mechanism, and a likely contributor to tissue aging. Cellular senescence involves extensive cellular remodeling, including of chromatin structure. Autophagy and lysosomes are
Adams   +100 more
core   +2 more sources

Key regulators of vascular calcification in chronic kidney disease: Hyperphosphatemia, BMP2, and RUNX2 [PDF]

open access: yesPeerJ
Vascular calcification is quite common in patients with end-stage chronic kidney disease and is a major trigger for cardiovascular complications in these patients.
Xinhua Liang   +3 more
doaj   +2 more sources

Morphometric studies of chloroquine induced autophagy in rat liver [PDF]

open access: green, 1979
Ann Marie Wisner-Gebhart   +2 more
openalex   +1 more source

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