Results 121 to 130 of about 523,293 (245)

Autophagy in Neurons

open access: yesAnnual Review of Cell and Developmental Biology, 2019
Autophagy is the major cellular pathway to degrade dysfunctional organelles and protein aggregates. Autophagy is particularly important in neurons, which are terminally differentiated cells that must last the lifetime of the organism. There are both constitutive and stress-induced pathways for autophagy in neurons, which catalyze the turnover of aged ...
Erika L.F. Holzbaur, Andrea K.H. Stavoe
openaire   +3 more sources

The relationship between HBV antigens deposition in kidneys and renal prognosis in IgA nephropathy patients infected with HBV

open access: yesRenal Failure
Background Hepatitis B virus (HBV) is a risk factor for the progression of immunoglobulin A (IgA) nephropathy. The effect of HBV antigens deposition in kidneys and treatment influencing HBV deposition requires further investigation.Methods We analyzed ...
Yun Guo   +4 more
doaj   +1 more source

Protective Effect of SMAD‐Specific E3 Ubiquitin Protein Ligase 1 in Alcoholic Steatohepatitis in Mice

open access: yesHepatology Communications, 2019
Excessive accumulation of lipids in the liver is crucial in the pathogenesis of alcoholic steatohepatitis and may be partly mediated by impaired degradation of lipid droplets by autophagy. The E3 ubiquitin ligase SMAD‐specific E3 ubiquitin protein ligase
Jan Petrasek   +2 more
doaj   +1 more source

Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites

open access: yesNature Communications, 2019
Centrosomes drive mitotic spindle formation and chromosome segregation. Here, the authors show that centrosome stability is regulated by selective autophagic degradation of centriolar satellite components in a process they term doryphagy, connecting ...
Søs Grønbæk Holdgaard   +27 more
doaj   +1 more source

Autophagy in the liver [PDF]

open access: yesJournal of Hepatology, 2013
Patrice Codogno, Alfred J. Meijer
openaire   +2 more sources

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