Results 141 to 150 of about 373,644 (316)
Renal FailureBackground Hepatitis B virus (HBV) is a risk factor for the progression of immunoglobulin A (IgA) nephropathy. The effect of HBV antigens deposition in kidneys and treatment influencing HBV deposition requires further investigation.Methods We analyzed ...
Yun Guo +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni +13 more
wiley +1 more source
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
, 2013 [[sponsorship]]生物醫學科學研究所[[note]]已出版;[SCI];有審查制度;不具代表性[[note]]http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Drexel&SrcApp=hagerty_opac&KeyRecord=1554-8627&DestApp=JCR&RQ=IF_CAT_BOXPLOT[[note]]http://gateway.isiknowledge.com ...
Klionsky, DJ;Abdalla, FC;Abeliovich, H;Abraham, RT;Acevedo-Arozena, A;Adeli, K;Agholme, L;Agnello, M;Agostinis, P;Aguirre-Ghiso, JA;Ahn, HJ;Ait-Mohamed, O;Ait-Si-Ali, S;Akematsu, T;Akira, S;Al-Younes, HM;Al-Zeer, MA;Albert, ML;Albin, RL;Alegre-Abarrategui, J;Aleo, MF;Alirezaei, M;Almasan, A;Almonte-Becerril, M;Amano, A;Amaravadi, R;Amarnath, S;Amer, AO;Andrieu-Abadie, N;Anantharam, V;Ann, DK;Anoopkumar-Dukie, S;Aoki, H;Apostolova, N;Arancia, G;Aris, JP;Asanuma, K;Asare, NY;Ashida, H;Askanas, V;Askew, DS;Auberger, P;Baba, M;Backues, SK;Baehrecke, EH;Bahr, BA;Bai, XY;Bailly, Y;Baiocchi, R;Baldini, G;Balduini, W;Ballabio, A;Bamber, BA;Bampton, ET;Bánhegyi, G;Bartholomew, CR;Bassham, DC;Bast Jr, RC;Batoko, H;Bay, BH;Beau, I;Béchet, DM;Begley, TJ;Behl, C;Behrends, C;Bekri, S;Bellaire, B;Bendall, LJ;Benetti, L;Berliocchi, L;Bernardi, H;Bernassola, F;Besteiro, S;Bhatia-Kissova, I;Bi, X;Biard-Piechaczyk, M;Blum, JS;Boise, LH;Bonaldo, P;Boone, DL;Bornhauser, BC;Bortoluci, KR;Bossis, I;Bost, F;Bourquin, JP;Boya, P;Boye
core
Advanced Healthcare Materials, EarlyView.Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha +9 more
wiley +1 more source
Autophagy Stimulation as a Potential Strategy Against Intestinal Fibrosis
, 2019 We recently observed reduced autophagy in Crohn’s disease patients and an anti-inflammatory effect of autophagy stimulation in murine colitis, but both anti- and pro-fibrotic effects are associated with autophagy stimulation in different tissues ...
Francisco Canet +9 more
core +1 more source
Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities
Advanced Science, EarlyView.ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal +3 more
wiley +1 more source
Autophogy Protects Neuron from a Beta-Induced Cytotoxicity
, 2010 Autophagy is a degradation pathway for the turnover of dysfunctional organelles or aggregated proteins in cells. Extracellular accumulation of P-amyloid peptide has been reported to be a major cause of Alzheimer disease (AD) and large numbers of ...
洪詩雅;黃偉邦;劉鴻祺;符文美 +1 more
core
Autophagy in Neurotrauma: Good, Bad, or Dysregulated
, 2019 Autophagy is a physiological process that helps maintain a balance between the manufacture of cellular components and breakdown of damaged organelles and other toxic cellular constituents.
Marta M. Lipinski, Junfang Wu
core +1 more source
Advanced Science, EarlyView.Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu +12 more
wiley +1 more source
A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase
Advanced Science, EarlyView.Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol +18 more
wiley +1 more source