Results 171 to 180 of about 687,627 (397)

Autophagy

Biochimica et biophysica acta-Molecular basis of disease, 2009
Degradation processes are important for optimal functioning of eukaryotic cells. The two major protein degradation pathways in eukaryotes are the ubiquitin-proteasome pathway and autophagy. This contribution focuses on autophagy. This process is important for survival of cells during nitrogen starvation conditions but also has a house keeping function ...
Todde, V., Veenhuis, M, van der Klei, I.J.   +2 more
openaire   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Evasion of autophagy mediated by Rickettsia surface protein OmpB is critical for virulence. [PDF]

, 2019
Rickettsia are obligate intracellular bacteria that evade antimicrobial autophagy in the host cell cytosol by unknown mechanisms. Other cytosolic pathogens block different steps of autophagy targeting, including the initial step of polyubiquitin-coat ...
Burke, Thomas P, Cox, Jeffery S, Engström, Patrik, Golovkine, Guillaume, Iavarone, Anthony T, Ingabire, Nadia, Mark, Kevin G, Mitchell, Gabriel, Rape, Michael, Welch, Matthew D   +9 more
core  

HTT/Huntingtin in selective autophagy and Huntington disease: A foe or a friend within? [PDF]

, 2015
Yan‐Ning Rui, Zhen Xu, Bindi Patel, Ana María Cuervo, Sheng Zhang   +4 more
openalex   +1 more source

Autophagy Is a Crucial Path in Chondrogenesis of Adipose-Derived Mesenchymal Stromal Cells Laden in Hydrogel [PDF]

, 2022
Elena Gabusi, Enrico Lenzi, Cristina Manferdini, Paolo Dolzani, Marta Columbaro, Yasmin Saleh, Gina Lisignoli   +6 more
openalex   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Adipose tissue autophagy status in obesity: Expression and flux—two faces of the picture [PDF]

, 2015
Hedi Soussi, Karine Clément, Isabelle Dugail   +2 more
openalex   +1 more source

Intrinsically Disordered Protein‐Inspired Nanovector‐Based Coacervates for the Direct Cytosolic Transport of Biomacromolecules

Advanced Materials, EarlyView.
Intrinsically disordered protein‐inspired nanovectors (IDP‐NVs) form stable nanocoacervates (NCs) with diverse biomacromolecules. In situ conformational changes confer stability and adaptability to NCs under dynamically changing physiological conditions.
Soyeong Jin, Hyemin Park, Seuk‐Min Ryu, Dagyeong Guk, Jaeeun Lee, Seongeon Jin, Changjoon Keum, Jinyoung Park, Myoung‐Hwan Park, Chaekyu Kim, Hojun Kim, Jaegeun Noh, Kwan Hyi Lee, Ja‐Hyoung Ryu, Youngdo Jeong   +14 more
wiley   +1 more source

Rescue of myogenic defects in Rb-deficient cells by inhibition of autophagy or by hypoxia-induced glycolytic shift [PDF]

, 2010
Giovanni Ciavarra, Eldad Zacksenhaus
openalex   +1 more source

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Nature Cell Biology, 2011
Joungmok Kim, M. Kundu, B. Viollet, K. Guan   +3 more
semanticscholar   +1 more source