Results 211 to 220 of about 449,405 (356)

Defective autophagy leads to cancer [PDF]

, 2003
Aimee L. Edinger, Craig B. Thompson
openalex   +1 more source

Activation of Lysosomal Retrograde Transport Triggers TPC1‐IP3R1 Ca2+ Crosstalk at Lysosome‐ER MCSs Leading to Lethal Depleting of ER Calcium

Advanced Science, EarlyView.
The flavonoid compound LW‐213 exerts its antitumor effects through a novel mechanism involving lysosomal‐ER calcium regulation. Specifically, LW‐213 binds to LIMP2, which induces perinuclear clustering of lysosomes and facilitates calcium‐mediated lysosome‐ER interactions.
Meng‐yuan Zhu, Yong‐jian Guo, Yu‐qi Zhu, Hong‐zheng Wang, Hai‐di Wang, Hong‐yu Chen, Yue‐xin Jiang, Hui Li, Hui Hui   +8 more
wiley   +1 more source

Histone H4K16 acetylation modification regulated autophagy and apoptosis in neuron after spinal cord injury. [PDF]

Sci Rep
Lin JM, Li KH, Zhou LQ, Chen DH, Zhao X, Li WW, Liu WG.   +6 more
europepmc   +1 more source

Autophagy and the cvt Pathway Both Depend on AUT9

, 2000
Thomas Lang, Steffen Reiche, Michael Straub, Monika Bredschneider, Michael Thumm   +4 more
openalex   +2 more sources

Autophagy is induced during cell death by incompatibility and is essential for differentiation in the filamentous fungus Podospora anserina [PDF]

, 2003
Bérangère Pinan‐Lucarré, Mathieu Paoletti, Karine Dementhon, Bénédicte Coulary‐Salin, Corinne Clavé   +4 more
openalex   +1 more source

D‐glucuronyl C5‐Epimerase Binds to EGFR to Suppress Kidney Fibrosis

Advanced Science, EarlyView.
Glucuronyl C5‐epimerase (Hsepi, gene name Glce) is a key enzyme catalyzing heparan sulfate (HS) chain biosynthesis in HS proteoglycans, which are ubiquitously expressed on cell membranes. In normal renal tubular cells, Glce binds to the intracellular domains of EGFR, maintaining stable and orderly EGFR phosphorylation.
Xiaoqi Jing, Jun Wu, Jingru Ning, Xiaoyu Ding, Zhenyun Du, Xiaojiang Wang, Lulin Huang, Ran Wang, Changlin Mei, Kan Ding   +9 more
wiley   +1 more source

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene [PDF]

, 2003
X. Qu
openalex   +1 more source

Steroid Receptor Coactivator‐1 Drives Tumor‐Associated Macrophage Reprogramming by Mediating MMP12 Transcription in Pancreatic Cancer Perineural Invasion

Advanced Science, EarlyView.
Steroid receptor coactivator‐1 (SRC‐1) reprograms tumor‐associated macrophages (TAMs) via signal transducer and activator of transcription 1(STAT1)‐mediated matrix metallopeptidase 12 (MMP12) transcription to drive perineural invasion (PNI) in pancreatic cancer.
Ke Cheng, Liang Liu, Miaomiao Gong, Yuke Ji, Chunmei Bai, Xiangqian Guo, Hui Chen, Jinjin Pan, Ying Zhang, Yuhui Yuan   +9 more
wiley   +1 more source

BECLIN-1/BECN1 at the barrier: a gatekeeper of epithelial and endothelial homeostasis. [PDF]

Autophagy Rep
Juliani J, Fairlie WD, Lee EF.
europepmc   +1 more source

Class III phosphoinositide 3-kinase–Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes [PDF]

, 2003
Amina Tassa, Marie Paule ROUX, Didier Attaix, Daniel Béchet   +3 more
openalex   +1 more source