Results 231 to 240 of about 517,228 (307)
Editorial: Unlocking autophagy's full potential: embracing a multidimensional approach for targeted cancer treatment. [PDF]
Wiersma VR.
europepmc +1 more source
Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu +8 more
wiley +1 more source
Autophagy-Independent Function of ATG-18 Is Essential for Gonadal Longevity in Caenorhabditis elegans. [PDF]
Shioda T +13 more
europepmc +1 more source
Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie +17 more
wiley +1 more source
Polydatin Relieves Airway Remodeling by Inhibiting P2X7R-NLRP3-Mediated Excessive Autophagy in Asthma. [PDF]
Li G +8 more
europepmc +1 more source
Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats [PDF]
Bové +42 more
core +2 more sources
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren +5 more
wiley +1 more source

