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Biomarkers, oxidative stress and autophagy in skin aging
Ageing Research Reviews, 2020Aging is a major cause of many degenerative diseases. The most intuitive consequence of aging is mainly manifested on the skin, resulting in cumulative changes in skin structure, function and appearance, such as increased wrinkles, laxity, elastosis, telangiectasia, and aberrant pigmentation of the skin.
Yanpei, Gu +3 more
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Exploring biomarkers for autophagy‐mediated macrophage pyroptosis in atherosclerosis
Cell Biology International, 2023AbstractThis study tried to investigate the macrophage autophagy‐related pyroptosis in atherosclerosis. The gene expression omnibus (GEO) dataset of GSE100927 was used for differentially expressed genes (DEG) screening, gene ontology (GO) and kyoto encyclopedia of genes and genomes (KEGG), CIBERSORT, weighted correlation network analysis (WGCNA ...
Rongyuan Yang +3 more
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2021
Biomarkers (short for biological markers) are biological measures of a biological state. Autophagy biomarkers play an important role as an indicator of autophagy during normal physiological processes, pathogenic processes or pharmacological responses to drugs.
Fang, Lin, Yu-Ting, Zhu, Zheng-Hong, Qin
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Biomarkers (short for biological markers) are biological measures of a biological state. Autophagy biomarkers play an important role as an indicator of autophagy during normal physiological processes, pathogenic processes or pharmacological responses to drugs.
Fang, Lin, Yu-Ting, Zhu, Zheng-Hong, Qin
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Autophagy biomarkers in patients with acute myocardial infarction
European Heart Journal, 2022Abstract Introduction Acute myocardial infarction (AMI) is still one of leading cause for mortality and disability in cardiovascular disease [1]. Autophagy is an intracellular mechanism involved in the elimination and the recycling of proteins and organelles by lysosomes [2].
M G Kong +4 more
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A novel signature of autophagy-related immunophenotyping biomarkers in osteoarthritis
Life Sciences, 2023We aimed to provide an autophagy-related signature to seek immunophenotyping biomarkers in osteoarthritis (OA).Microarray expression profiling of OA subchondral bone samples and screening of an autophagy database for autophagy-related differentially expressed genes (au-DEGs) between OA and normal samples were performed.
Liyu, Yang +3 more
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Multi-omics approaches identify novel prognostic biomarkers of autophagy in uveal melanoma
Journal of Cancer Research and Clinical Oncology, 2023Uveal melanoma (UVM) is a rare yet malignant ocular tumor that metastases in approximately half of all patients, with the majority of those developing metastasis typically succumbing to the disease within a year. Hitherto, no effective treatment for UVM has been identified.
Wenke, Jin +6 more
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A Study on Autophagy Related Biomarkers in Alzheimer’s Disease Based on Bioinformatics
Cellular and Molecular Neurobiology, 2023Alzheimer's disease (AD) is a neurodegenerative disease with an annual incidence increase that poses significant health risks to people. However, the pathogenesis of AD is still unclear. Autophagy, as an intracellular mechanism can degrade damaged cellular components and abnormal proteins, which is closely related to AD pathology. The goal of this work
Jian, Li +5 more
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Experimental Dermatology, 2023
Abstract Abnormal death of neutrophils and the subsequent ineffective clearance of cell fragments result in production of autoantigens that can lead to systemic lupus erythematosus (SLE). Excessive formation of neutrophil extracellular traps (NETs) can trigger the synthesis of pro‐inflammatory cytokines such as type I interferons ...
Mingfang Li +4 more
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Abstract Abnormal death of neutrophils and the subsequent ineffective clearance of cell fragments result in production of autoantigens that can lead to systemic lupus erythematosus (SLE). Excessive formation of neutrophil extracellular traps (NETs) can trigger the synthesis of pro‐inflammatory cytokines such as type I interferons ...
Mingfang Li +4 more
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Abstract P1050: The Activity Of Autophagy Biomarkers In Acute Myocardial Infarction
Circulation Research, 2023Purpose: We aimed to evaluate the activity of autophagy in patients with AMI. Furthermore, this study analyzed the associations of autophagy biomarkers with the traditional cardiac biomarkers, echocardiographic left ventricular ejection fraction (LVEF) and the defect size of myocardial SPECT ...
Min Gyu Kong +4 more
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May Autophagy be a Novel Biomarker and Antitumor Target in Colorectal Cancer?
Biomarkers in Medicine, 2016Autophagy is a catabolic process associated with intracellular self-digestion of damaged organelles or redundant proteins enabling maintenance of cell homeostasis. It is accepted that impaired autophagy is closely linked to cancer development and has been extensively studied in a variety of malignancies including colorectal cancer (CRC) to elucidate ...
Justyna, Gil +2 more
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