Results 41 to 50 of about 39,411 (265)

The contribution of autopsy in COVID-19 pandemic: Missed opportunity in Sub-Saharan Africa

open access: yesForensic Science International: Reports, 2020
‘Autopsy studies are for the living and not the dead!’ This statement underlines the central role of autopsy studies in refining and informing the medical and forensic science body of knowledge.Significant outbreaks, like the ongoing COVID-19 pandemic ...
William F. Mawalla
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

The hospital autopsy: the importance in keeping autopsy an option

open access: yesAutopsy and Case Reports, 2022
Autopsy has been one of the most powerful diagnostic tools in medicine for over a century. Despite its importance in establishing cause of death and elucidating pathophysiology of disease, rates of hospital autopsies continue to decline.
Rachel Scarl   +4 more
doaj  

The characteristics of thoracic aortic dissection in autopsy-diagnosed individuals: An autopsy study [PDF]

open access: gold, 2022
Qianhao Zhao   +10 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Report and Recommendations of the Association of Pathology Chairs’ Autopsy Working Group

open access: yesAcademic Pathology, 2018
Autopsy has been a foundation of pathology training for many years, but hospital autopsy rates are notoriously low. At the 2014 meeting of the Association of Pathology Chairs, some pathologists suggested removing autopsy from the training curriculum of ...
Gregory G. Davis MD, MSPH   +13 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

THE AIDS PATIENT SUFFERING FROM GENERALIZED MYCOBACTERIOSIS

open access: yesТуберкулез и болезни лёгких, 2015
The clinical case of mycobacteriosis caused by drug resistant strains of M. avium (subspecies of hominissuis), was observed in the patient su}ering from HIV at the stage of AIDS.
T. F. Otten   +4 more
doaj  

Molecular Genetic Characteristics of Mycobacterium tuberculosis Isolates from Patients with HIV-Associated Tuberculosis

open access: yesТуберкулез и болезни лёгких
The objective: to provide molecular genetic characteristics of Mycobacterium tuberculosis isolates from patients with HIV-associated tuberculosis.Subjects and Methods. Two groups of M.
A. A. Gerasimova   +4 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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