Results 101 to 110 of about 110,609 (237)

Plant‐Derived Melatonin Inhibits Bacterial Virulence via CpxA/R Two‐Component System

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Plant‐derived melatonin is sensed by CpxAE48/T51, which inhibits the phosphorylation cascade transmission from CpxAH240 to CpxRD52, resulting in the inhibition of DNA‐binding capacity of CpxR and subsequent T3SS genes expression in Pst DC3000. ABSTRACT In defending against pathogens, plants deploy diverse secondary metabolites and signaling molecules ...
Jin‐Wei Wei, Wei Liu, Bili Cao, Dan Zhao, Chengqiang Wang, Xin Hou, Tangyuan Ning, Biao Gong   +7 more
wiley   +1 more source

Complementarity of radioautographic and immunohistochemical techniques for localizing neuroreceptors at the light and electron microscopy level

Brazilian Journal of Medical and Biological Research, 1998
To assess relationships between neuropeptide-binding sites and receptor proteins in rat brain, the distribution of radioautographically labeled somatostatin and neurotensin-binding sites was compared to that of immunolabeled sst2A and NTRH receptor ...
Beaudet A.
doaj  

A Novel Closo-Ortho-Carborane-Based Glucosamine Derivative as a Promising Agent for Boron Neutron Capture Therapy

Pharmaceuticals
Background: Boron Neutron Capture Therapy (BNCT) is a promising cancer treatment that combines tumor-selective boron delivery agents with thermal neutrons to kill cancer cells while sparing normal tissue.
Daniela Imperio, Ian Postuma, Salvatore Villani, Erika Del Grosso, Laura Cansolino, Cinzia Ferrari, Silvia Fallarini, Silva Bortolussi, Luigi Panza   +8 more
doaj   +1 more source

Emerging directions in tauopathy research

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract The Tau Global Conference 2025, hosted by the Alzheimer's Association, CurePSP, and the Rainwater Charitable Foundation, convened international experts from academia, industry, government, and philanthropy to explore advances and challenges in tauopathy research. The meeting highlighted progress across tau biology, including emerging models of
Luc Buée, Kristin R. Wildsmith, Suvarna Alladi, Taylor Bertucci, Delphine Boche, Kathryn R. Bowles, Adam Boxer, Jennifer Brummet, Sarah L. DeVos, Kristophe Diaz, Anna Jane Dreyer, Karen Duff, Claudia Duran‐Aniotz, Claire S. Durrant, Kurt Farrell, Igor C. Fontana, Nicolai Franzmeier, Bess Frost, Kanta Horie, Petr Kaňovský, Aimee W. Kao, Simin Mahinrad, Maura Malpetti, Huw R. Morris, Carla Palleis, Leonard Petrucelli, Jessica Rexach, Larisa Reyderman, Amy Rommel, James B. Rowe, Sandra M. Sanabria Bohórquez, Chihiro Sato, Michael Schöll, Anja Schneider, Rohan de Silva, Heather M. Snyder, Lawren VandeVrede, Andrew W. Varga, Jacob W. Vogel, Felix L. Yeh, Andrew S. Yoo, Maria C. Carrillo   +41 more
wiley   +1 more source

Autoradiography with silicon strip detectors

, 1996
A digital autoradiography system based on double sided silicon strip detectors (1.6x1.6 mm(2) active surface with 100 mu m pitch) has been developed and successfully tested with beta-emitting tracers.
Tripiccione R, Grossi G, TAIBI, Angelo, Caria M, Marziani M, Stefanini A, DEL GUERRA, ALBERTO, Beccherle R, FANTACCI ME, Russo P, BISOGNI MG, ROSSO V, GAMBACCINI, Mauro, Bertolucci E, Gambaccini M, ROSSO, VALERIA, Amendolia SR, FANTACCI, MARIA EVELINA, Taibi A, MARZIANI, Michele, Conti M, Madonna G, Marchesini R, Randaccio P, TRIPICCIONE, Raffaele, BISOGNI, MARIA GIUSEPPINA, Bottigli U, Mancini E, DELGUERRA A   +28 more
core   +2 more sources

Mu Opioid Receptor mRNA and Protein Localization Across the Rat and Mouse Habenula

Journal of Comparative Neurology, Volume 534, Issue 6, June 2026.
Mu opioid receptor (MOR) mRNA was detected with RNAscope in situ hybridization for Oprm1 and protein was detected with immunocytochemistry to map the distributions across the anterior‐posterior extent of the rat and mouse habenula. Expression distribution was also characterized in a transgenic reporter mouse line (Oprm1‐Venus/Venus) as an additional ...
Aashka K. Popat, Rhiana C. Simon, Beatriz B. Aoyama, Ahana Wokhlu, Aliza T. Ehrlich, Corey C. Harwell, Elyssa B. Margolis   +6 more
wiley   +1 more source

Image processing methods in digital autoradiography.

, 2002
Autoradiography is a common method in biomedical research for detecting and measuring biodistributions of labelled biomolecules within a specimen. The conventional method is based on using film or film-emulsions for the image acquisition.
Kokkinou, Eleni.
core  

The Recycling Endosomal (Na+, K+)/H+ Exchanger NHE6/SLC9A6 Facilitates Signal Transduction by Shuttling Cyclin‐Dependent Kinase 5 to the Plasma Membrane

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The alkali cation/proton exchanger NHE6/SLC9A6 regulates luminal pH homeostasis and trafficking of recycling endosomes in most tissues, especially neurons. Loss‐of‐function mutations in NHE6 cause Christianson Syndrome, an X‐linked neurodevelopmental and neurodegenerative disorder; however, the underlying molecular and cellular mechanisms ...
Rebecca Flessner, Alina Ilie, Léo Han, Annie Boucher, Rebecca Anne McKinney, Reza Sharif‐Naeini, John Orlowski   +6 more
wiley   +1 more source

Autoradiography

, 2014
Author: Dr. William H. Heidcamp ### Materials 1. ^3H-Thymidine, specific activity of 2.0 - curie/millimole - Onion sets, jars and toothpicks - Alcohol-acetic acid fixative - Materials for feulgen reaction (Exercise 2.4) - Paraffin embedding, sectioning equipment - Kodak Nuclear Track Emulsion (or equivalent) - Darkroom - Water bath at 42° C - Kodak ...
openaire   +2 more sources

The Development and Application of Tritium-Labeled Compounds in Biomedical Research

Molecules
With low background radiation, tritiate compounds exclusively emit intense beta particles without structural changes. This makes them a useful tool in the drug discovery arsenal.
Yu Teng, Hong Yang, Yulin Tian
doaj   +1 more source