The Development and Application of Tritium-Labeled Compounds in Biomedical Research
With low background radiation, tritiate compounds exclusively emit intense beta particles without structural changes. This makes them a useful tool in the drug discovery arsenal.
Yu Teng, Hong Yang, Yulin Tian
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Measurement of Cell Adhesion and Migration Using Phosphor-Screen Autoradiography
This study demonstrates the use of phosphor-screen autoradiography as a means of measuring cell adhesion and cell expansion on polymer surfaces.
B.A. Dalton+4 more
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Localization of axonally transported 125I-wheat germ agglutinin beneath the plasma membrane of chick retinal ganglion cells. [PDF]
The distribution of 125I-wheat germ agglutinin (WGA) transported by axons of chick retinal ganglion cells to layer d of the optic tectum was studied by electron microscopic autoradiography.
LaVail, JH, McDonald, DM, Sugino, IK
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Autoradiography of End-plates with Carbon-14 – Calabash – Curarine I and Carbon-14 – Decamethonium [PDF]
Peter G. Waser, Urs Lüthi
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Autoradiography of microgels [PDF]
Dirk-Ingo Wolfrum+2 more
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In vitro characterization of [125I]HY-3-24, a selective ligand for the dopamine D3 receptor
IntroductionDopamine D3 receptor (D3R) ligands have been studied for the possible treatment of neurological and neuropsychiatric disorders. However, selective D3R radioligands for in vitro binding studies have been challenging to identify due to the high
Ji Youn Lee+6 more
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Rapid synthesis and turnover of brain microsomal ether phospholipids in the adult rat
The rates of synthesis, turnover, and half-lives were determined for brain microsomal ether phospholipids in the awake adult unanesthetized rat. A multicompartmental kinetic model of phospholipid metabolism, based on known pathways of synthesis, was ...
Thad A. Rosenberger+4 more
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A Bayesian Hierarchical Approach to Quasi-Replicate Dataset Modelling
It is very common for multiple experiments to be conducted under non-identical but similar conditions, perhaps because of implementation errors, natural variability in experimental material, or gradual drifting of experimental conditions. In the extremes
Hassan M. Aljohani, Robert G. Aykroyd
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Phosphorylation of Spinophilin Modulates Its Interaction with Actin Filaments [PDF]
Spinophilin is a protein phosphatase 1 (PP1)- and actin-binding protein that modulates excitatory synaptic transmission and dendritic spine morphology. We report that spinophilin is phosphorylated in vitro by protein kinase A (PKA).
Allen, Patrick B.+5 more
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