Results 251 to 260 of about 193,799 (312)

Development of a Novel <sup>18</sup>F-Labeled Radioligand for Imaging Phosphodiesterase 7 with Positron Emission Tomography. [PDF]

open access: yesMol Pharm
Rong J   +19 more
europepmc   +1 more source

Nonphotographic Alpha Autoradiography and Neutron-Induced Autoradiography [PDF]

open access: possibleScience, 1970
With a new combination of two techniques, (i) alpha-particle or fission fragment registration in thin polymer foils by etching and (ii) automatic counting and magnification of the etched perforations by local evaporation of a thin metal layer with an electric spark, the sensitivity of conventional photographic methods for determining quantity and ...
Klaus Becker, D. R. Johnson
openaire   +2 more sources
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Autoradiography and Phosphorimaging

Cold Spring Harbor Protocols, 2020
Many of the commonly used techniques in molecular cloning depend on methods to map accurately the distribution of radioactive atoms on two-dimensional (2D) surfaces. Without this ability, methods such as Southern blotting, northern hybridizations, radiolabeled DNA sequencing, and library screening would not have been possible.
Michael R. Green, Joseph Sambrook
openaire   +3 more sources

Quantitative whole-body autoradiography: past, present and future.

Bioanalysis, 2015
Traditional bioanalytical measurements determine concentrations of drug and metabolites in plasma; however, most drugs exert their effects in defined target tissues.
A. Mcewen, C. Henson
semanticscholar   +1 more source

Neurotransmitter receptor localization: from autoradiography to imaging mass spectrometry.

ACS Chemical Neuroscience, 2015
Autoradiography is used to determine the anatomical distribution of biological molecules in human tissue and experimental animal models. This method is based on the analysis of the specific binding of radiolabeled compounds to locate neurotransmitter ...
I. Manuel   +6 more
semanticscholar   +1 more source

Speciation of radioactive soil particles in the Fukushima contaminated area by IP autoradiography and microanalyses.

Environmental Science and Technology, 2014
Radioactive soil particles several tens of micrometers in size were collected from litter soil in the radiation contaminated area by the Fukushima nuclear plant accident and characterized using electron and X-ray microanalyses.
H. Mukai   +5 more
semanticscholar   +1 more source

Use of radioactive compounds and autoradiography to determine drug tissue distribution.

Chemical Research in Toxicology, 2012
Radioactivity has been used in drug discovery and development for several decades because it offers researchers a highly sensitive way to quantitatively assess the absorption, distribution, metabolism, and/or excretion (ADME) of chemical entities by ...
E. Solon
semanticscholar   +1 more source

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