Results 51 to 60 of about 103,352 (315)

Revisiting Target‐Aware de novo Molecular Generation with TarPass: Between Rational Design and Texas Sharpshooter

open access: yesAdvanced Science, EarlyView.
TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin   +11 more
wiley   +1 more source

Forecasting techniques based on absolute difference for small dataset to predicttheSET Indexin Thailand

open access: yesEngineering and Applied Science Research, 2018
This research aims to use asimple statistical method asa forecasting model with a small dataset. Absolute difference methods, average absolute difference and minimum absolute difference, were used to adjust the dataset, i.e., the SET Index ...
Watcharin Klongdee, Mathee Pongkitwitoon
doaj   +1 more source

Combining Spatial Multi‐Omics Data to Decipher Spatial Domains and Elucidate Cell Heterogeneity Based on Self‐Supervised Graph Learning

open access: yesAdvanced Science, EarlyView.
A self‐supervised multi‐view graph fusion framework integrates spatial multi‐omics, excelling in domain identification and denoising. It reconstructs spatial pseudo‐expression, jointly analyzes multi‐omics data, infers RNA velocity, predicts spatial omics features from single‐cell multi‐omics, and detects spatially dark genes and transcription factors,
Yuejing Lu   +8 more
wiley   +1 more source

Fuzzy Autoregressive Model With an Application [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2009
The research is dedicated in the study to time series and the ability of using fuzzy logic with it in order to develop forecasting approaches. In this research ,the time series (Autoregressive model) are linked with fuzzy logic in order to get on the ...
doaj   +1 more source

Using a Language Model to Generate Music in Its Symbolic Domain While Controlling Its Perceived Emotion

open access: yesIEEE Access, 2023
This work proposes a transformer-based model capable of generating music in its symbolic domain, in a controllable fashion. The ultimate goal of this is to build a system with which people can compose music collaboratively with a computer.
Naomi Imasato   +3 more
doaj   +1 more source

From Label‐Free Multiphoton Imaging to Pathological Reports: A Vision‐Language Breast Cancer Margin Pathological Diagnosis System

open access: yesAdvanced Science, EarlyView.
MarginPath is a novel vision‐language system that automates breast cancer margin assessment using a single label‐free multiphoton microscopy image. By integrating tumor‐associated collagen signatures with virtual H&E imaging, it generates accurate margin heatmaps and comprehensive diagnostic reports.
Shu Wang   +15 more
wiley   +1 more source

Diagnostics 101: A Tutorial for Fault Diagnostics of Rolling Element Bearing Using Envelope Analysis in MATLAB

open access: yesApplied Sciences, 2020
This paper presents a MATLAB-based tutorial to conduct fault diagnosis of a rolling element bearing. While there have been so many new developments in this field, no studies have addressed the tutorial aspects in this field to help the engineers learn ...
Seokgoo Kim, Dawn An, Joo-Ho Choi
doaj   +1 more source

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

open access: yesAdvanced Science, EarlyView.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li   +10 more
wiley   +1 more source

Error Mitigation Algorithm Based on Bidirectional Fitting Method for Collision Avoidance of Unmanned Surface Vehicle

open access: yesPolish Maritime Research, 2018
Radars and sensors are essential devices for an Unmanned Surface Vehicle (USV) to detect obstacles. Their precision has improved significantly in recent years with relatively accurate capability to locate obstacles. However, small detection errors in the
Song Lifei   +4 more
doaj   +1 more source

The Grid Bootstrap and the Autoregressive Model [PDF]

open access: yesReview of Economics and Statistics, 1999
A “grid” bootstrap method is proposed for confidence-interval construction, which has improved performance over conventional bootstrap methods when the sampling distribution depends upon the parameter of interest. The basic idea is to calculate the bootstrap distribution over a grid of values of the parameter of interest and form the confidence ...
openaire   +2 more sources

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