Results 111 to 120 of about 98,858 (333)

Type 2 diabetes and depression via microvascular dysfunction, neurodegeneration, inflammation, advanced glycation end products (AGEs), and arterial stiffness

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Type 2 diabetes increases the risk of depression, but the mechanisms underlying this association are incompletely understood. We investigated whether microvascular dysfunction, neurodegeneration, low‐grade inflammation, advanced glycation end products (AGEs) and arterial stiffness, pathologies that are more common in diabetes, explain, or
Indra L. M. Steens   +10 more
wiley   +1 more source

Cerebral vasoreactivity in response to a headof-bed position change is altered in patients with moderate and severe obstructive sleep apnea [PDF]

open access: yes, 2018
Obstructive sleep apnea (OSA) can impair cerebral vasoreactivity and is associated with an increased risk of cerebrovascular disease. Unfortunately, an easy-to-use, non-invasive, portable monitor of cerebral vasoreactivity does not exist. Therefore, we
Blanco, Igor   +9 more
core   +4 more sources

Cerebral autoregulation dynamics in humans.

open access: yesStroke, 1989
We studied the response of cerebral blood flow to acute step decreases in arterial blood pressure noninvasively and nonpharmacologically in 10 normal volunteers during normocapnia, hypocapnia, and hypercapnia.
R. Aaslid   +3 more
semanticscholar   +1 more source

A somatic multiple myeloma mutation unravels a mechanism of oligomerization‐mediated product inhibition in GGPPS

open access: yesThe FEBS Journal, EarlyView.
Geranylgeranyl diphosphate synthase (GGPPS) plays a key role in multiple myeloma biology. Using crystallography, mass spectrometry, and fluorescence spectroscopy, this study shows that a somatic multiple myeloma cell line mutation destabilizes inter‐dimer interactions, resulting in increased GGPPS activity by facilitating product releas.
Ruba Yehia   +7 more
wiley   +1 more source

Photoplethysmography for Quantitative Assessment of Sympathetic Nerve Activity (SNA) During Cold Stress [PDF]

open access: yes, 2019
The differences in the degree of sympathetic nerve activity (SNA) over cutaneous blood vessels, although known to be more prominent in the periphery than the core vasculature, has not been thoroughly investigated quantitatively.
Ainslie   +43 more
core   +2 more sources

Prolonged monitoring of cerebral blood flow and autoregulation with diffuse correlation spectroscopy in neurocritical care patients

open access: yesNeurophotonics, 2018
. Monitoring of cerebral blood flow (CBF) and autoregulation are essential components of neurocritical care, but continuous noninvasive methods for CBF monitoring are lacking.
J. Selb   +10 more
semanticscholar   +1 more source

Multi‐omics analysis reveals discordant proteome and transcriptome responses in larval guts of Frankliniella occidentalis infected with an orthotospovirus

open access: yesInsect Molecular Biology, EarlyView.
Tomato spotted wilt virus modulated the abundance of gut proteins in larval thrips, most notably manifested as a predominant down‐regulation in first instar larvae. Gut‐expressed protein and cognate transcript abundance were moderately correlated across the tissue system; however, the virus effect varied widely at transcriptional and translational ...
Jinlong Han, Dorith Rotenberg
wiley   +1 more source

Positive autoregulation of GDNF levels in the ventral tegmental area mediates long-lasting inhibition of excessive alcohol consumption. [PDF]

open access: yes, 2011
Glial cell line-derived neurotrophic factor (GDNF) is an essential growth factor for the survival and maintenance of the midbrain dopaminergic (DA-ergic) neurons.
Ahmadiantehrani, S   +3 more
core   +3 more sources

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont   +5 more
wiley   +1 more source

Tripartite Symbiosis Between Legumes, Arbuscular Mycorrhizal Fungi and Nitrogen Fixing Rhizobia: Interactions and Regulation

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Legume plants can interact with nitrogen‐fixing rhizobia bacteria and arbuscular mycorrhizal fungi (AMF) simultaneously, forming a tripartite symbiotic association. Co‐inoculation studies performed on a variety of legumes have shown that rhizobia and AMF influence each other when they co‐occur in tripartite association and affect host plant ...
Polyxeni Gorgia, Daniela Tsikou
wiley   +1 more source

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