Results 121 to 130 of about 41,213 (279)
Experimental Physiology, EarlyView.Abstract Reductions in brain insulin sensitivity and cerebral blood flow (CBF) have emerged as potential factors contributing to Alzheimer's disease and related dementia. However, no work has tested whether a single bout of exercise can raise brain insulin sensitivity in at‐risk adults. The aim of the study was to test whether a single bout of exercise
Steven K. Malin +4 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A sudden decrease in total peripheral resistance (TPR), as observed during vasovagal syncope, leads to a reduction in aortic systolic pressure (AO pressure) and afterload. In healthy individuals, the consequent decrease in left ventricular systolic pressure (LV pressure) lowers stroke work and myocardial energy expenditure.
Martin Dvoulety, Michal Sitina
wiley +1 more source
Astrocytes: Orchestrators of brain gas exchange and oxygen homeostasis
The Journal of Physiology, EarlyView.Abstract figure legend Oxygen and carbon dioxide enter the body via breathing; in the brain astrocytes play a key role balancing oxygen delivery with carbon dioxide removal. Abstract If we consider neurons like muscles during exercise, the demand for oxygen (O2) and carbon dioxide (CO2) elimination is constantly changing.
Isabel N. Christie
wiley +1 more source
Temporal autoregulation during human PU.1 locus SubTAD formation [PDF]
, 2018 Daniel Schuetzmann +18 more
openalex +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley +1 more source
TFC6 (TFIIIC subunit): a bridge between prokaryotic and eukaryotic gene regulation.
Frontiers in Genetics, 2012 Michèle eAMOUYAL
doaj +1 more source
Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?
Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Longitudinal assessment of sex differences in cerebrovascular ageing over a ∼6 year period: the Brain in Motion study. Cerebrovascular function was assessed at baseline (T1) and at a follow‐up (T2) ∼6 years later, at rest, during euoxic hypercapnia and while engaging in submaximal exercise. Over the follow‐up period females had a
Connor Snow +10 more
wiley +1 more source