Results 111 to 120 of about 30,053 (265)

Cystic kidney diseases: many ways to form a cyst [PDF]

, 2012
Renal cysts are a common radiological finding in both adults and children. They occur in a variety of conditions, and the clinical presentation, management, and prognosis varies widely.
Loftus, H., Ong, A.C.M.
core   +1 more source

Human asthenozoospermia: Update on genetic causes, patient management, and clinical strategies

Andrology, Volume 13, Issue 5, Page 1044-1064, July 2025.
Abstract Background In mammals, sperm fertilization potential relies on efficient progression within the female genital tract to reach and fertilize the oocyte. This fundamental property is supported by the flagellum, an evolutionarily conserved organelle, which contains dynein motor proteins that provide the mechanical force for sperm propulsion and ...
Emma Cavarocchi, Maëva Drouault, Joao C. Ribeiro, Violaine Simon, Marjorie Whitfield, Aminata Touré   +5 more
wiley   +1 more source

Activation of PIEZO1 Attenuates Kidney Cystogenesis In Vitro and Ex Vivo

Kidney360
Key Points. PIEZO1 activation reduces cystogenesis: Yoda1 activates PIEZO1, raising calcium and lowering cAMP, reducing cyst growth in autosomal dominant polycystic kidney disease models.
Qingfeng Fan, Mohamad Hadla, Zack Peterson, Grace Nelson, Hong Ye, Xiaofang Wang, Jean Marc Mardirossian, Peter C. Harris, Seth L. Alper, Y.S. Prakash, Arthur Beyder, Vicente E. Torres, Fouad T. Chebib   +12 more
doaj   +1 more source

European ADPKD Forum multidisciplinary position statement on autosomal dominant polycystic kidney disease care [PDF]

, 2017
Autosomal dominant polycystic kidney disease (ADPKD) is a chronic, progressive condition characterised by the development and growth of cysts in the kidneys and other organs and by additional systemic manifestations.
Alastair Kent, Albert C M Ong, Brenda de Coninck, Denis Clément, Dorien Peters, Elena Levtchenko, Hendrik Van Poppel, Joost P H Drenth, José Luis Górriz, Klemens Budde, Lorenzo E Derchi, Marianna Eleftheroudi, null null, null null, null null, Olivier Devuyst, Raymond Vanholder, Richard Sandford, Ron T Gansevoort, Tess Harris, Tevfik Ecder, Vicente E Torres, Yves Pirson   +22 more
core   +6 more sources

TRPP2 and autosomal dominant polycystic kidney disease

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007
Mutations in TRPP2 (polycystin-2) cause autosomal dominant polycystic kidney disease (ADPKD), a common genetic disorder characterized by progressive development of fluid-filled cysts in the kidney and other organs. TRPP2 is a Ca(2+)-permeable nonselective cation channel that displays an amazing functional versatility at the cellular level.
openaire   +3 more sources

The Vertebrate Breed Ontology: Toward Effective Breed Data Standardization

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background Limited universally‐adopted data standards in veterinary medicine hinder data interoperability and therefore integration and comparison; this ultimately impedes the application of existing information‐based tools to support advancement in diagnostics, treatments, and precision medicine.
Kathleen R. Mullen, Imke Tammen, Nicolas A. Matentzoglu, Marius Mather, James P. Balhoff, Elizabeth Esdaile, Gregoire Leroy, Carissa A. Park, Halie M. Rando, Nadia T. Saklou, Tracy L. Webb, Nicole A. Vasilevsky, Christopher J. Mungall, Melissa A. Haendel, Frank W. Nicholas, Sabrina Toro   +15 more
wiley   +1 more source

Renal cell carcinoma in autosomal dominant polycystic kidney disease: A case report

Radiology Case Reports, 2023
Autosomal dominant polycystic kidney disease (ADPKD) is one of the congenital cystic renal diseases with the highest incidence. ADPKD was suspected of being a risk factor for the emergence of RCC.
Gullyawan Rooseno, Ida Bagus Gde Tirta Yoga Yatindra, Wahjoe Djatisoesanto, Tarmono Djojodimedjo   +3 more
doaj  

Results of kidney transplantation in patients with end-stage renal failure caused by autosomal dominant polycystic kidney disease

Вестник трансплантологии и искусственных органов, 2019
Aim. To investigate the renal transplantation results for patients with end-stage renal disease (ESRD) due to autosomal dominant polycystic kidney disease (PKD).Materials and methods.
V. S. Daineko, A. N. Ananiev, E. S. Nevirovich, A. E. Skvorcov, S. A. Budylev, А. N. Selivanov, M. M. Moskalenko, V. A. Manukovskiy, O. N. Reznik   +8 more
doaj   +1 more source

Renin-Angiotensin-Aldosterone System Antagonism and Polycystic Kidney Disease Progression. [PDF]

, 2016
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a systemic disease characterised by the formation of multiple renal cysts that adversely affect renal function.
Hian, Chuan Kai, Lee, Chin Liang, Thomas, Warren   +2 more
core   +2 more sources

Polycystic kidney disease: Clues to pathogenesis [PDF]

, 1991
Autosomal-dominant polycystic kidney disease (ADPKD), largely neglected for several decades, has emerged in recent years as the renal disease most likely to be understood from the gene to the patient.
Gabow, Patricia A.
core   +1 more source